Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1801394
rs1801394
0.040 GeneticVariation BEFREE Results of this study showed that the rs1801394 alone or together with the rs1801133 is not a risk factor for CRC in Iranian population. 28691890

2017

dbSNP: rs1801394
rs1801394
0.040 GeneticVariation BEFREE Our pooled data suggest an association between MTRR A66G polymorphism and CRC susceptibility among Caucasians. 26214647

2015

dbSNP: rs1801394
rs1801394
0.040 GeneticVariation BEFREE A total of 41 (17,552 cases and 26,238 controls), 24(8,263 cases and 12,033 controls), 12(3,758 cases and 5,646 controls), and 13 (5,511 cases and 7,265 controls) studies were finally included for the association between methylenetetrahydrofolate reductase (MTHFR) C677T and A1289C, methione synthase reductase (MTRR) A66G, methionine synthase (MTR) A2756G polymorphisms and the risk of CRC, respectively. 22719222

2012

dbSNP: rs1801394
rs1801394
0.040 GeneticVariation BEFREE This population-based case-control study was designed to investigate the interrelationships between polymorphisms in the methylenetetrahydrofolate (MTHFR C677T and A1298C) gene and other genes (MTR A2756G; MTRR A66G and CBS 844ins68), intake of B-vitamins and colorectal cancer risk (CRC). 12020105

2002

dbSNP: rs10380
rs10380
0.010 GeneticVariation BEFREE In the present study, we have assessed the association of six polymorphisms and relative haplotypes in the MTHFR gene (rs1801133 and rs1801131) and in the MTRR gene (rs1801394, rs1532268, rs162036, and rs10380) with the risk for colorectal cancer in 666 patients and 1377 controls from the Czech Republic. 21211571

2011

dbSNP: rs162036
rs162036
0.010 GeneticVariation BEFREE In the present study, we have assessed the association of six polymorphisms and relative haplotypes in the MTHFR gene (rs1801133 and rs1801131) and in the MTRR gene (rs1801394, rs1532268, rs162036, and rs10380) with the risk for colorectal cancer in 666 patients and 1377 controls from the Czech Republic. 21211571

2011