Gene: CRP ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1130864
rs1130864
CRP
0.020 GeneticVariation BEFREE The present case control study investigated the contribution of three relevant CRP single nucleotide polymorphisms: -717A>G located in the promoter region (rs2794521), +1059G>C on exon2 (rs1800947) and +1444C>T in the 3' UTR (rs1130864) in 180 angiographically verified CHD cases and 175 control subjects. 24965144

2014
dbSNP: rs2794521
rs2794521
CRP
0.020 GeneticVariation BEFREE Minor allele frequencies (G, C and T) of rs2794521, rs1800947 and rs1130864 are observed to be 21.1, 11.7, 29.4 and 11.4, 10.0, 19.7 % in CHD cases and controls respectively. 24965144

2014
dbSNP: rs2794521
rs2794521
CRP
0.020 GeneticVariation BEFREE These results provided functional evidence supporting the association of the SNP rs2794521 of the CRP gene with CHD probably through regulating the expression level of CRP by different variations of rs2794521. 19624831

2009
dbSNP: rs1130864
rs1130864
CRP
0.020 GeneticVariation BEFREE We found no association of a genetic variant, which is known to be related to CRP levels, (rs1130864) and having CHD. 18714384

2008
dbSNP: rs77832441
rs77832441
CRP
0.010 GeneticVariation BEFREE Despite a strong effect on CRP levels, rs77832441 was not associated with inflammation-related phenotypes including coronary heart disease. 25187575

2015
dbSNP: rs1800947
rs1800947
CRP
0.010 GeneticVariation BEFREE The present case control study investigated the contribution of three relevant CRP single nucleotide polymorphisms: -717A>G located in the promoter region (rs2794521), +1059G>C on exon2 (rs1800947) and +1444C>T in the 3' UTR (rs1130864) in 180 angiographically verified CHD cases and 175 control subjects. 24965144

2014
dbSNP: rs3091244
rs3091244
CRP
0.010 GeneticVariation BEFREE Post hoc analysis suggests that the AA genotype of the triallelic SNP rs3091244, after adjustment for covariates, was associated with prevalent coronary heart disease in the non-Hispanic white population sample. 17101857

2006
dbSNP: rs748954737
rs748954737
CRP
0.010 GeneticVariation BEFREE The E23K gene polymorphism in Kir6.2 gene appeared to be related to high susceptibility to CHD. 16455067

2006