Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.060 | GeneticVariation | BEFREE | The current meta-analysis suggests that M235T polymorphism might be associated with increased risk of heart failure in Caucasians. | 23154270 | 2014 |
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0.060 | GeneticVariation | BEFREE | The pooled data showed that there was no significant associations between the AGT M235T polymorphism and HF</span> risk for TT vs. MM (OR = 1.17, 95%CI = 0.62-2.19, P = 0.635), MT vs. MM (OR = 0.97, 95%CI = 0.77-1.22, P = 0.776), MT/TT vs. MM (OR = 1.07, 95%CI = 0.67-1.69, P = 0.781), and TT vs. MM/MT (OR = 1.23, 95%CI = 0.86-1.76, P = 0.259). | 24572548 | 2014 |
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0.060 | GeneticVariation | BEFREE | To investigate a role of AGT G(-6)A and M235T genetic variants for chronic heart failure (CHF) and advanced atherosclerosis (AA), a total of 240 patients with CHF and 200 patients with AA of the Czech origin were evaluated for the study. | 20945963 | 2011 |
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0.060 | GeneticVariation | BEFREE | Angiotensinogen M235T and T174M gene polymorphisms in combination doubles the risk of mortality in heart failure. | 17145981 | 2007 |
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0.060 | GeneticVariation | BEFREE | Association of two angiotensinogen gene polymorphisms, M235T and G(-6)A, with chronic heart failure. | 12767551 | 2003 |
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0.060 | GeneticVariation | BEFREE | The DD allele frequency is lower in Chinese, but the M235T variant of the angiotensinogen gene is more common in Chinese than whites; it is not known to what extent polymorphisms of the renin-angiotensin system affect clinical status or prognosis in Chinese patients with heart failure. | 10097225 | 1999 |
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0.010 | GeneticVariation | BEFREE | This study suggested that angiotensinogen gene variants M235T and T174M may provide prognostic information for long-term survival in heart failure patients. | 17145981 | 2007 |