Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121918467
rs121918467
PTPN11
T 0.700 CausalMutation CLINVAR

dbSNP: rs1276519904
rs1276519904
H3-3A
G 0.700 GeneticVariation CLINVAR

dbSNP: rs1555968941
rs1555968941
CACNA1C
C 0.700 GeneticVariation CLINVAR

dbSNP: rs1565679039
rs1565679039
COL2A1
A 0.700 CausalMutation CLINVAR

dbSNP: rs199469465
rs199469465
SRCAP
T 0.700 CausalMutation CLINVAR

dbSNP: rs886040971
rs886040971
TRPS1
A 0.700 CausalMutation CLINVAR

dbSNP: rs10736303
rs10736303
FGFR2
0.010 GeneticVariation BEFREE Five SNPs (rs2162540, rs2981578, rs1078806, rs11200014, and rs10736303) were found to be associated with skeletal malocclusions (all <i>P</i> < 0.05). 31509720

2019
dbSNP: rs372127537
rs372127537
FGF7 ; FAM227B
0.010 GeneticVariation BEFREE The associations of common and rare variants with MP as a categorical phenotype and also continuous malocclusion phenotypes generated by principal component (PC) analysis were analyzed.One common variant, rs372127537, located in the 3'-untranslated region of FGF7 gene, was significantly related to PC1 (P  =  4.22 × 10), which explained 23.23% of the overall phenotypic variation observed and corresponded to vertical discrepancies ranging from short anterior face height to long anterior face height, after Bonferroni correction. 28640125

2017
dbSNP: rs104894396
rs104894396
GJB2
0.010 GeneticVariation BEFREE The case particularities are: the correlation between malocclusion and Waardenburg syndrome due to hypoplastic alae nasi and also factors that produced hearing loss, which could be Waardenburg syndrome, Usher syndrome or the presence of the connexin 26 (W24X) gene mutation. 26429191

2015
dbSNP: rs1815739
rs1815739
ACTN3
0.010 GeneticVariation BEFREE ACTN3 R577X genotypes associate with Class II and deepbite malocclusions. 25439211

2014