Gene: KIT ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519703
rs1057519703
KIT
T 0.700 CausalMutation CLINVAR The GIST of targeted therapy for malignant melanoma. 24531699

2014
dbSNP: rs1057519703
rs1057519703
KIT
T 0.700 CausalMutation CLINVAR Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations. 24661573

2014
dbSNP: rs1057519705
rs1057519705
KIT
G 0.700 CausalMutation CLINVAR Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations. 24661573

2014
dbSNP: rs1057519705
rs1057519705
KIT
G 0.700 CausalMutation CLINVAR The GIST of targeted therapy for malignant melanoma. 24531699

2014
dbSNP: rs1057519706
rs1057519706
KIT
G 0.700 CausalMutation CLINVAR Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations. 24661573

2014
dbSNP: rs1057519706
rs1057519706
KIT
G 0.700 CausalMutation CLINVAR The GIST of targeted therapy for malignant melanoma. 24531699

2014
dbSNP: rs1057519708
rs1057519708
KIT
A 0.700 CausalMutation CLINVAR The GIST of targeted therapy for malignant melanoma. 24531699

2014
dbSNP: rs1057519708
rs1057519708
KIT
A 0.700 CausalMutation CLINVAR Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations. 24661573

2014
dbSNP: rs121913517
rs121913517
KIT
C 0.700 GeneticVariation CLINVAR A meta-analysis of somatic mutations from next generation sequencing of 241 melanomas: a road map for the study of genes with potential clinical relevance. 24755198

2014
dbSNP: rs121913517
rs121913517
KIT
G 0.700 CausalMutation CLINVAR Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations. 24661573

2014
dbSNP: rs121913517
rs121913517
KIT
C 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913517
rs121913517
KIT
G 0.700 CausalMutation CLINVAR The GIST of targeted therapy for malignant melanoma. 24531699

2014
dbSNP: rs121913517
rs121913517
KIT
A 0.700 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913521
rs121913521
KIT
A 0.700 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913524
rs121913524
KIT
C 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913685
rs121913685
KIT
G 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs1057519713
rs1057519713
KIT
C 0.700 CausalMutation CLINVAR Secondary c-Kit mutations confer acquired resistance to RTK inhibitors in c-Kit mutant melanoma cells. 23582185

2013
dbSNP: rs1057519704
rs1057519704
KIT
A 0.700 CausalMutation CLINVAR Activating c-KIT mutations in a subset of thymic carcinoma and response to different c-KIT inhibitors. 22357254

2012
dbSNP: rs121913235
rs121913235
KIT
C 0.700 CausalMutation CLINVAR Sunitinib therapy for melanoma patients with KIT mutations. 22261812

2012
dbSNP: rs121913235
rs121913235
KIT
A 0.700 CausalMutation CLINVAR Sunitinib therapy for melanoma patients with KIT mutations. 22261812

2012
dbSNP: rs121913514
rs121913514
KIT
G 0.700 CausalMutation CLINVAR [Secondary mutation of c-kit/PDGFRα genotypes after imatinib mesylate therapy and its relationship with efficacy of sunitinib]. 22932406

2012
dbSNP: rs121913523
rs121913523
KIT
A 0.700 GeneticVariation CLINVAR [Secondary mutation of c-kit/PDGFRα genotypes after imatinib mesylate therapy and its relationship with efficacy of sunitinib]. 22932406

2012
dbSNP: rs121913523
rs121913523
KIT
C 0.700 CausalMutation CLINVAR [Secondary mutation of c-kit/PDGFRα genotypes after imatinib mesylate therapy and its relationship with efficacy of sunitinib]. 22932406

2012
dbSNP: rs200375589
rs200375589
KIT
T 0.700 CausalMutation CLINVAR High KIT and PDGFRA are associated with shorter patients survival in gastroenteropancreatic neuroendocrine tumors, but mutations are a rare event. 22160160

2012
dbSNP: rs200375589
rs200375589
KIT
C 0.700 CausalMutation CLINVAR High KIT and PDGFRA are associated with shorter patients survival in gastroenteropancreatic neuroendocrine tumors, but mutations are a rare event. 22160160

2012