| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
T | 0.750 | CausalMutation | CLINVAR | Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype. | 22808163 | 2012 |
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|
T | 0.750 | CausalMutation | CLINVAR | Activating Q209L/P mutations in GNAQ or GNA11 (GNAQ/11) are present in approximately 80% of uveal melanomas. | 22733540 | 2012 |
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|
C | 0.750 | CausalMutation | CLINVAR | Activating Q209L/P mutations in GNAQ or GNA11 (GNAQ/11) are present in approximately 80% of uveal melanomas. | 22733540 | 2012 |
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|
C | 0.750 | CausalMutation | CLINVAR | Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype. | 22808163 | 2012 |
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|
T | 0.750 | CausalMutation | CLINVAR | Mutations in GNA11 in uveal melanoma. | 21083380 | 2010 |
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|
C | 0.750 | CausalMutation | CLINVAR | Mutations in GNA11 in uveal melanoma. | 21083380 | 2010 |
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|
C | 0.750 | CausalMutation | CLINVAR | Mutated alpha subunit of the Gq protein induces malignant transformation in NIH 3T3 cells. | 1328859 | 1992 |
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|
T | 0.750 | CausalMutation | CLINVAR | Mutated alpha subunit of the Gq protein induces malignant transformation in NIH 3T3 cells. | 1328859 | 1992 |
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|
T | 0.750 | CausalMutation | CLINVAR | GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. | 2549426 | 1989 |
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|
C | 0.750 | CausalMutation | CLINVAR | GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. | 2549426 | 1989 |