Gene: RAD51L3-RFFL ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1064795045
rs1064795045
RAD51D ; RAD51L3-RFFL
A 0.700 GeneticVariation CLINVAR

dbSNP: rs1210620444
rs1210620444
RAD51D ; RAD51L3-RFFL
T 0.700 GeneticVariation CLINVAR

dbSNP: rs1403784434
rs1403784434
RAD51D ; RAD51L3-RFFL
A 0.700 GeneticVariation CLINVAR Detection of Germline Mutations in Patients with Epithelial Ovarian Cancer Using Multi-gene Panels: Beyond BRCA1/2. 29020732

2018
dbSNP: rs1403784434
rs1403784434
RAD51D ; RAD51L3-RFFL
A 0.700 GeneticVariation CLINVAR Individualized iterative phenotyping for genome-wide analysis of loss-of-function mutations. 26046366

2015
dbSNP: rs1409088398
rs1409088398
RAD51D ; RAD51L3-RFFL
TG 0.700 GeneticVariation CLINVAR

dbSNP: rs1555567202
rs1555567202
RAD51D ; RAD51L3-RFFL
T 0.700 GeneticVariation CLINVAR

dbSNP: rs1555567610
rs1555567610
RAD51D ; RAD51L3-RFFL
GA 0.700 GeneticVariation CLINVAR RAD51 protein ATP cap regulates nucleoprotein filament stability. 22275364

2012
dbSNP: rs1555567610
rs1555567610
RAD51D ; RAD51L3-RFFL
GA 0.700 GeneticVariation CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251

2015
dbSNP: rs1555567610
rs1555567610
RAD51D ; RAD51L3-RFFL
GA 0.700 GeneticVariation CLINVAR Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer. 25452441

2015
dbSNP: rs1555567649
rs1555567649
RAD51D ; RAD51L3-RFFL
C 0.700 GeneticVariation CLINVAR Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2. 27616075

2017
dbSNP: rs1555568386
rs1555568386
RAD51D ; RAD51L3-RFFL
G 0.700 GeneticVariation CLINVAR

dbSNP: rs1555568514
rs1555568514
RAD51D ; RAD51L3-RFFL
G 0.700 GeneticVariation CLINVAR

dbSNP: rs1555570242
rs1555570242
RAD51D ; RAD51L3-RFFL
T 0.700 GeneticVariation CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251

2015
dbSNP: rs1555570242
rs1555570242
RAD51D ; RAD51L3-RFFL
T 0.700 GeneticVariation CLINVAR Inherited Mutations in Women With Ovarian Carcinoma. 26720728

2016
dbSNP: rs370228071
rs370228071
RAD51D ; RAD51L3-RFFL
C 0.700 GeneticVariation CLINVAR

dbSNP: rs370228071
rs370228071
RAD51D ; RAD51L3-RFFL
A 0.700 GeneticVariation CLINVAR Functionally Null RAD51D Missense Mutation Associates Strongly with Ovarian Carcinoma. 28646019

2017
dbSNP: rs370228071
rs370228071
RAD51D ; RAD51L3-RFFL
A 0.700 GeneticVariation CLINVAR Loss of function germline mutations in RAD51D in women with ovarian carcinoma. 22986143

2012
dbSNP: rs370228071
rs370228071
RAD51D ; RAD51L3-RFFL
A 0.700 GeneticVariation CLINVAR Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequential Series of Patients With Breast Cancer. 26976419

2016
dbSNP: rs370228071
rs370228071
RAD51D ; RAD51L3-RFFL
A 0.700 GeneticVariation CLINVAR Germline mutation in the RAD51B gene confers predisposition to breast cancer. 24139550

2013
dbSNP: rs370228071
rs370228071
RAD51D ; RAD51L3-RFFL
A 0.700 GeneticVariation CLINVAR Disparate requirements for the Walker A and B ATPase motifs of human RAD51D in homologous recombination. 16717288

2006
dbSNP: rs561425038
rs561425038
RAD51D ; RAD51L3-RFFL
A 0.700 GeneticVariation CLINVAR

dbSNP: rs587782848
rs587782848
RAD51D ; RAD51L3-RFFL
G 0.700 GeneticVariation CLINVAR Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. 6329717

1982
dbSNP: rs587782848
rs587782848
RAD51D ; RAD51L3-RFFL
G 0.700 GeneticVariation CLINVAR The ATPase motif in RAD51D is required for resistance to DNA interstrand crosslinking agents and interaction with RAD51C. 16236763

2005
dbSNP: rs750219200
rs750219200
RAD51D ; RAD51L3-RFFL
T 0.700 GeneticVariation CLINVAR

dbSNP: rs750621215
rs750621215
RAD51D ; RAD51L3-RFFL
A 0.700 GeneticVariation CLINVAR Germline Mutations in Cancer Susceptibility Genes in a Large Series of Unselected Breast Cancer Patients. 28724667

2017