rs1044498
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Our study pointed out the role of MC4R rs17782313 and ENPP1 rs1044498 genotypes in obesity determinisms in mothers and their newborns in correlation with BMI, MUAC, TST and bioimpedance parameters.
|
31350533 |
2019 |
rs1044498
|
|
|
0.040 |
GeneticVariation |
BEFREE |
However, we found no association of ENPP1 rs1044498 with obesity (BMI ≧ 27 kg/m(2)).
|
27238374 |
2016 |
rs1044498
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Findings from the previous studies have suggested a relationship between ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP-1) or plasma cell membrane glycoprotein 1 (PC-1) gene single nucleotide polymorphism (K121Q, rs1044498) and genetic susceptibility to obesity.
|
21565692 |
2011 |
rs1044498
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In addition, the previously reported ENPP1/PC-1 "risk haplotype" (Q (rs1044498), delT (rs1799774), and G (rs7754561) alleles) was found to be associated with obesity in male, but not in female, subjects (P = 0.035).
|
18719658 |
2008 |
rs7754561
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Furthermore, we found nominal associations between obesity risk or BMI variation and the following SNPs: ENPP1 rs7754561, MC4R rs17782313 and NEGR1 rs2815752.
|
23375129 |
2013 |
rs7754561
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In addition, the previously reported ENPP1/PC-1 "risk haplotype" (Q (rs1044498), delT (rs1799774), and G (rs7754561) alleles) was found to be associated with obesity in male, but not in female, subjects (P = 0.035).
|
18719658 |
2008 |
rs997509
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Because insulin resistance is a pivotal factor in the development of metabolic syndrome (MS) and impaired glucose tolerance (IGT), we aimed to test the association between the K121Q and rs997509 ENPP-1 variants with obesity, MS and IGT in obese children and adolescents.
|
18940878 |
2009 |
rs1799774
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, the previously reported ENPP1/PC-1 "risk haplotype" (Q (rs1044498), delT (rs1799774), and G (rs7754561) alleles) was found to be associated with obesity in male, but not in female, subjects (P = 0.035).
|
18719658 |
2008 |
rs943003
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Weaker associations were detected between the SNPs rs1541276 in the MC5R, rs1926065 in the MC3R genes and obesity (P = 0.04 and P = 0.03, respectively), and between SNPs rs2236700 in the MC5R, rs2118404 in the POMC, rs943003 in the ENPP1 genes and type 2 diabetes (P = 0.03, P = 0.02 and P = 0.02, respectively); these associations did not, however, remain significant after correction for multiple testing.
|
18551113 |
2008 |