|
rs1800571
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In addition, the impact of total energy intake on obesity in Pro12Ala</span> carriers seemed to be stronger than that in the wild-type genotype carriers.
|
30122193 |
2018 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In addition, the impact of total energy intake on obesity in Pro12Ala</span> carriers seemed to be stronger than that in the wild-type genotype carriers.
|
30122193 |
2018 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To further elucidate the role of genetics in obesity onset, we performed a candidate-gene association study in a young and sportive Italian population by testing the association of functional polymorphisms in ACE (rs4646994), FTO (rs9939609), MC4R (rs17782313) and PPARG (rs1801282) genes with body mass index (BMI) and waist-to-height ratio (WHtR).
|
28090739 |
2017 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our results support an important association between rs1805192 minor allele (G allele) of PPARG and increased DN risk; the interaction analysis showed a combined effect of interaction between rs1805192 and abdominal obesity on DN risk.
|
28013303 |
2017 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our results support an important association between rs1805192 and rs3856806 minor allele (G allele) of PPARG and increased T2DM risk, the interaction analysis shown a combined effect of G- obesity interaction between rs1805192 and obesity on increased T2DM risk.
|
28123453 |
2017 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
When T2D cohort was further stratified according to the obesity status, PPARγ2 (rs1801282) and FTO (rs9939609) showed association with T2D only in the obese diabetic group and ADIPOQ (rs16861194) showed no difference in risk of susceptibility to the disease.
|
26243686 |
2016 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Moreover, the combination of the rs2282440-SDC3T/T genotype with the rs1801282-peroxisome proliferator-activated receptor-gamma2 gene (PPARγ2) G carrier genotype was strongly associated with obesity (OR=6.77).
|
27515755 |
2016 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The measured parameters for mothers and their newborns were risk percentage for child obesity, anthropometric characteristics (mid-upper arm circumference [MUAC], tricipital skinfold thickness [TST] of mother and newborn), genetic polymorphisms (human peroxisome proliferator-activated receptor γ [PPARγ2] 34 C > G and transforming growth factor-beta 1 [TGF-β1] 869 T > C gene polymorphisms in both mothers and newborns), and mother's bioimpedance characteristics (fat mass [FM] %).The obesity risk score according to standard predictable Northern Finland Birth Cohort equation was in our study 4.07%.
|
27442659 |
2016 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The measured parameters for mothers and their newborns were risk percentage for child obesity, anthropometric characteristics (mid-upper arm circumference [MUAC], tricipital skinfold thickness [TST] of mother and newborn), genetic polymorphisms (human peroxisome proliferator-activated receptor γ [PPARγ2] 34 C > G and transforming growth factor-beta 1 [TGF-β1] 869 T > C gene polymorphisms in both mothers and newborns), and mother's bioimpedance characteristics (fat mass [FM] %).The obesity risk score according to standard predictable Northern Finland Birth Cohort equation was in our study 4.07%.
|
27442659 |
2016 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The combined results showed that PPAR-γ Pro1</span>2Ala polymorphism was associated with the obesit</span>y risk (Ala vs.
|
25502405 |
2015 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the relationship between functional polymorphisms Gly482Ser in PPARGC1A and Pro12Ala in PPARG2 with the presence of obesity and metabolic risk factors.
|
26185753 |
2015 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Polymorphisms of the peroxisome proliferator-activated receptor-γ (rs1801282) and its coactivator-1 (rs8192673) are associated with obesity indexes in subjects with type 2 diabetes mellitus.
|
25928419 |
2015 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The PPARG rs1801282 SNP did not exhibit any significant association with obesity among the complete sample population.
|
25182148 |
2015 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Obesity and Pro12Ala Polymorphism of Peroxisome Proliferator-Activated Receptor-Gamma Gene in Healthy Adults: A Systematic Review and Meta-Analysis.
|
26361038 |
2015 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma (PPARG) gene in relation to obesity and metabolic phenotypes in a Taiwanese population.
|
25182148 |
2015 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The combined results showed that PPAR-γ Pro1</span>2Ala polymorphism was associated with the obesit</span>y risk (Ala vs.
|
25502405 |
2015 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Obesity and Pro12Ala Polymorphism of Peroxisome Proliferator-Activated Receptor-Gamma Gene in Healthy Adults: A Systematic Review and Meta-Analysis.
|
26361038 |
2015 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the relationship between functional polymorphisms Gly482Ser in PPARGC1A and Pro12Ala in PPARG2 with the presence of obesity and metabolic risk factors.
|
26185753 |
2015 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The single nucleotide polymorphisms (SNPs) of the above genes, such as GNB3-C825T, ADRB3-Trp64Arg, UCP2-3'UTR 45 bp del/ins, and PPARγ-Pro12Ala, are associated with obesity and body mass index.
|
24827746 |
2014 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the group with ACE DD genotype, those with PPARγ Pro12Ala or Ala12Ala genotype have greater odds for obesity (OR=9.98; 95% CI: 1.18-84.14, p=0.034).
|
24200052 |
2014 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Interaction between Pro12Ala polymorphism of PPARγ2 and diet on adiposity phenotypes.
|
25342491 |
2014 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome proliferator-activated receptor gamma 2 gene (PPARG2) rs1801282 polymorphisms are type 2 diabetes mellitus susceptibility gene variants associated with obesity.
|
24969838 |
2014 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Interaction between Pro12Ala polymorphism of PPARγ2 and diet on adiposity phenotypes.
|
25342491 |
2014 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The single nucleotide polymorphisms (SNPs) of the above genes, such as GNB3-C825T, ADRB3-Trp64Arg, UCP2-3'UTR 45 bp del/ins, and PPARγ-Pro12Ala, are associated with obesity and body mass index.
|
24827746 |
2014 |