DisGeNET - a database of gene-disease associations

Cerebrovascular accident, C0038454

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs556621

0.820

GeneticVariation

BEFREE

The variant rs556621 but not rs11984041 may increase susceptibility of LAA stroke in the Xinjiang Uyghur population.

25307434

2015

dbSNP:

rs2200733

0.820

GeneticVariation

BEFREE

Subsequently subgroup analysis indicated that both rs2200733 and rs10033464 conferred increased risk for cardioembolic stroke (CE str</span>oke) (for rs2200733, OR 1.38, 95 % CI 1.26-1.51; for rs10033464, OR 1.14, 95 % CI 1.02-1.26), while rs2200733 was marginal associated with non-CE stroke (OR 1.09, 95 % CI 1.02-1.16). our results demonstrated that two SNPs (rs2200733 and rs1003346) on chromosome 4q25 were limited to the stroke of cardioembolic etiology.

24065534

2013

dbSNP:

rs2200733

0.820

GeneticVariation

GWASDB

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke.

22306652

2012

dbSNP:

rs556621

0.820

GeneticVariation

GWASCAT

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke.

22941190

2012

dbSNP:

rs556621

0.820

GeneticVariation

GWASDB

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke.

22941190

2012

dbSNP:

rs2200733

0.820

GeneticVariation

BEFREE

The SNP rs2200733 on chromosome 4q25 is a risk factor for CE stroke related to AF only.

21574119

2011

dbSNP:

rs2200733

0.820

GeneticVariation

GWASDB

Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.

18991354

2008

dbSNP:

rs2200733

0.820

GeneticVariation

GWASCAT

Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.

18991354

2008

dbSNP:

rs1799963

0.810

GeneticVariation

GWASCAT

Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.

26908601

2016

dbSNP:

rs1799963

0.810

SusceptibilityMutation

CLINVAR

Prevalence and Geographical Variation of Prothrombin G20210A Mutation in Patients with Cerebral Vein Thrombosis: A Systematic Review and Meta-Analysis.

27031503

2016

dbSNP:

rs1799963

0.810

GeneticVariation

BEFREE

In multinomial multivariate adjusted analysis, rs1799963 was exclusively associated with undetermined stroke (OR: 3.67; 95% CI: 1.52-8.85; p = 0.004).

25897999

2015

dbSNP:

rs1799963

0.810

SusceptibilityMutation

CLINVAR

The genetics of venous thromboembolism. A meta-analysis involving approximately 120,000 cases and 180,000 controls.

19652888

2009

dbSNP:

rs1799963

0.810

SusceptibilityMutation

CLINVAR

The prothrombin 3'end formation signal reveals a unique architecture that is sensitive to thrombophilic gain-of-function mutations.

15059842

2004

dbSNP:

rs1799963

0.810

SusceptibilityMutation

CLINVAR

Increased efficiency of mRNA 3' end formation: a new genetic mechanism contributing to hereditary thrombophilia.

11443298

2001

dbSNP:

rs12646447

0.800

GeneticVariation

GWASCAT

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

24262325

2014

dbSNP:

rs12646447

0.800

GeneticVariation

GWASDB

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

24262325

2014

dbSNP:

rs161802

PARK7

0.800

GeneticVariation

GWASDB

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

24262325

2014

dbSNP:

rs161802

PARK7

0.800

GeneticVariation

GWASCAT

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

24262325

2014

dbSNP:

rs16851055

SPSB4

0.800

GeneticVariation

GWASDB

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

24262325

2014

dbSNP:

rs16851055

SPSB4

0.800

GeneticVariation

GWASCAT

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

24262325

2014

dbSNP:

rs17696736

NAA25

0.800

GeneticVariation

GWASCAT

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

24262325

2014

dbSNP:

rs17696736

NAA25

0.800

GeneticVariation

GWASDB

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

24262325

2014

dbSNP:

rs225132

0.800

GeneticVariation

GWASCAT

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

24262325

2014

dbSNP:

rs225132

0.800

GeneticVariation

GWASDB

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

24262325

2014

dbSNP:

rs13407662

ASB3

0.800

GeneticVariation

GWASCAT

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.

23041239

2012