|
rs11984041
|
|
|
0.830 |
GeneticVariation |
BEFREE |
The variant rs556621 but not rs11984041 may increase susceptibility of LAA stroke in the Xinjiang Uyghur population.
|
25307434 |
2015 |
|
rs11984041
|
|
|
0.830 |
GeneticVariation |
BEFREE |
A recent Genome-Wide Association study (GWAS) identified rs11984041 on HDAC9 gene to be significantly associated with stroke in a Caucasian population.
|
23828597 |
2013 |
|
rs11984041
|
|
|
0.830 |
GeneticVariation |
BEFREE |
We identified a new association for large vessel stroke within HDAC9 (encoding histone deacetylase 9) on chromosome 7p21.1 (including further replication in an additional 735 affected individuals and 28,583 controls) (rs11984041; combined P = 1.87 × 10(-11); odds ratio (OR) = 1.42, 95% confidence interval (CI) = 1.28-1.57).
|
22306652 |
2012 |
|
rs28688791
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The CC genotype of rs28688791 (P = 0.037) was also associated with moderate and severe stro</span>ke (NIHSS ≥ 6).
|
30565168 |
2019 |
|
rs28688791
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Apolipoprotein L1 (APOL1) rs73885319 (OR = 1.52; CI: 1.09-2.13, P-value = .013), rs2383207 in CDKN2A/CDKN2B (OR = 3.08; CI: 1.15-8.26, P -value = .026) and rs2107595 (OR = 1.70; CI: 1.12-2.60, P-value = .014) and rs28688791 (OR = 1.52; CI: 1.03-2.26, P-value = .036) in HDAC9 gene were associated with SVD stroke at 0.05 significance level.
|
28975602 |
2018 |
|
rs2389995
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Additionally, the rs2389995 (G/A) polymorphism was found to be significantly associated with a decreased risk of stroke in all genetic models.
|
28145521 |
2017 |
|
rs2389995
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Individuals with risk allele (A) for rs2389995 and (T) for rs2240419 had increased risk of stroke (odds ratio [OR] = 1.33, 95% confidence interval [CI]: 1.01-1.75; and OR = 1.29, 95% CI: 1.02-1.63), respectively.
|
23828597 |
2013 |
|
rs2074633
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, the CC genotype of rs2074633 and rs28688791 (rs2074633, P = 0.019; rs28688791, P = 0.023) showed significant association with unfavorable short-term outcome of LAA stroke.
|
30565168 |
2019 |
|
rs2240419
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Individuals with risk allele (A) for rs2389995 and (T) for rs2240419 had increased risk of stroke (odds ratio [OR] = 1.33, 95% confidence interval [CI]: 1.01-1.75; and OR = 1.29, 95% CI: 1.02-1.63), respectively.
|
23828597 |
2013 |