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rs121913294
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs2476601
|
|
|
0.030 |
GeneticVariation |
BEFREE |
No significant differences were observed for an association of TPO positivity or thyroid disease with single nucleotide polymorphisms in the INS, CTLA4, or VDR loci, with nominal significance (P=0.01) for PTPN22 R620W variant.
|
26405068 |
2015 |
|
rs2476601
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Association of Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) C1858T gene polymorphism with susceptibility to autoimmune thyroid diseases: a meta-analysis.
|
22374238 |
2012 |
|
rs2476601
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The R620W polymorphism of the protein tyrosine phosphatase 22 gene in autoimmune thyroid diseases and rheumatoid arthritis in the Tunisian population.
|
19343596 |
2009 |
|
rs27178
|
|
|
0.010 |
GeneticVariation |
BEFREE |
People with the TT allele in PDE4D (rs27178) should be made aware of an increased risk of subclinical thyroid disease.
|
30485936 |
2019 |
|
rs1130864
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the CRP rs1130864 A allele carrier state was significantly more frequent: (i) in BD patients with thyroid disorders than in those without (pc = 0.046), especially among females (pc = 0.01) and independently of lithium treatment, (ii) in BD patients with rapid cycling than in those without (pc = 0.004).
|
29352395 |
2018 |
|
rs1207011218
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Considering the implication of single-nucleotide polymorphisms (SNPs) in CTLA-4 gene expression and probably protein function, one can assume the involvement of these SNPs in neoplastic diseases. rs5742909 ( - 318C > T) and rs231775 ( + 49 A > G) are among the most commonly studied SNPs and have been considered as genetic factors related to thyroid diseases.
|
30078171 |
2018 |
|
rs179247
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis of chosen polymorphisms rs2476601 a/G - PTPN22, rs1990760 C/T - IFIH1, rs179247 a/G - TSHR in pathogenesis of autoimmune thyroid diseases in children.
|
29973096 |
2018 |
|
rs231775
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Considering the implication of single-nucleotide polymorphisms (SNPs) in CTLA-4 gene expression and probably protein function, one can assume the involvement of these SNPs in neoplastic diseases. rs5742909 ( - 318C > T) and rs231775 ( + 49 A > G) are among the most commonly studied SNPs and have been considered as genetic factors related to thyroid diseases.
|
30078171 |
2018 |
|
rs231775
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Considering the implication of single-nucleotide polymorphisms (SNPs) in CTLA-4 gene expression and probably protein function, one can assume the involvement of these SNPs in neoplastic diseases. rs5742909 ( - 318C > T) and rs231775 ( + 49 A > G) are among the most commonly studied SNPs and have been considered as genetic factors related to thyroid diseases.
|
30078171 |
2018 |
|
rs5742909
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Considering the implication of single-nucleotide polymorphisms (SNPs) in CTLA-4 gene expression and probably protein function, one can assume the involvement of these SNPs in neoplastic diseases. rs5742909 ( - 318C > T) and rs231775 ( + 49 A > G) are among the most commonly studied SNPs and have been considered as genetic factors related to thyroid diseases.
|
30078171 |
2018 |
|
rs6438552
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Besides, logistic regression analysis demonstrated that rs12716927, rs5498 and rs6438552 all would affect the influences exerted by age, BMI, smoking history, stressful work, stress at home, family history of thyroid disease or <sup>131</sup>I treatment on GO susceptibility (all P < 0.05).
|
29800560 |
2018 |
|
rs996807218
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Considering the implication of single-nucleotide polymorphisms (SNPs) in CTLA-4 gene expression and probably protein function, one can assume the involvement of these SNPs in neoplastic diseases. rs5742909 ( - 318C > T) and rs231775 ( + 49 A > G) are among the most commonly studied SNPs and have been considered as genetic factors related to thyroid diseases.
|
30078171 |
2018 |
|
rs2074451
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped six single-nucleotide polymorphisms (SNPs), rs6865453 in selenoprotein P gene (SELENOP), rs713041 rs2074451 rs3746165 in glutathione peroxidase 4 gene (GPX4) and rs28665122 and rs7178239 in selenoprotein S gene (SELENOS) by MassARRAY system using the chip-based matrix-assisted laser desorption ionization time-of-flight mass spectrometry technology in 1060 patients with autoimmune thyroid diseases and 938 healthy controls.
|
28499373 |
2017 |
|
rs28665122
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped six single-nucleotide polymorphisms (SNPs), rs6865453 in selenoprotein P gene (SELENOP), rs713041 rs2074451 rs3746165 in glutathione peroxidase 4 gene (GPX4) and rs28665122 and rs7178239 in selenoprotein S gene (SELENOS) by MassARRAY system using the chip-based matrix-assisted laser desorption ionization time-of-flight mass spectrometry technology in 1060 patients with autoimmune thyroid diseases and 938 healthy controls.
|
28499373 |
2017 |
|
rs3746165
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped six single-nucleotide polymorphisms (SNPs), rs6865453 in selenoprotein P gene (SELENOP), rs713041 rs2074451 rs3746165 in glutathione peroxidase 4 gene (GPX4) and rs28665122 and rs7178239 in selenoprotein S gene (SELENOS) by MassARRAY system using the chip-based matrix-assisted laser desorption ionization time-of-flight mass spectrometry technology in 1060 patients with autoimmune thyroid diseases and 938 healthy controls.
|
28499373 |
2017 |
|
rs6865453
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped six single-nucleotide polymorphisms (SNPs), rs6865453 in selenoprotein P gene (SELENOP), rs713041 rs2074451 rs3746165 in glutathione peroxidase 4 gene (GPX4) and rs28665122 and rs7178239 in selenoprotein S gene (SELENOS) by MassARRAY system using the chip-based matrix-assisted laser desorption ionization time-of-flight mass spectrometry technology in 1060 patients with autoimmune thyroid diseases and 938 healthy controls.
|
28499373 |
2017 |
|
rs713041
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped six single-nucleotide polymorphisms (SNPs), rs6865453 in selenoprotein P gene (SELENOP), rs713041 rs2074451 rs3746165 in glutathione peroxidase 4 gene (GPX4) and rs28665122 and rs7178239 in selenoprotein S gene (SELENOS) by MassARRAY system using the chip-based matrix-assisted laser desorption ionization time-of-flight mass spectrometry technology in 1060 patients with autoimmune thyroid diseases and 938 healthy controls.
|
28499373 |
2017 |
|
rs7178239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped six single-nucleotide polymorphisms (SNPs), rs6865453 in selenoprotein P gene (SELENOP), rs713041 rs2074451 rs3746165 in glutathione peroxidase 4 gene (GPX4) and rs28665122 and rs7178239 in selenoprotein S gene (SELENOS) by MassARRAY system using the chip-based matrix-assisted laser desorption ionization time-of-flight mass spectrometry technology in 1060 patients with autoimmune thyroid diseases and 938 healthy controls.
|
28499373 |
2017 |
|
rs7080536
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As a control cohort, 190 healthy individuals without known thyroid disease were also studied for the presence of the G534E variant using DNA isolated from peripheral leucocytes.
|
26906432 |
2016 |
|
rs4684677
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association between rs4684677 T/A polymorphism in preproghrelin gene and predisposition to autoimmune thyroid diseases in children.
|
25868387 |
2015 |
|
rs1217691063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Meta-analysis of nine studies showed that there was no association between MTHFR C677T polymorphism and thyroid diseases (OR (T vs. C) =1.09, 95% CI 0.94-1.26, p=0.25; OR (TT vs. CC) =1.04, 95% CI 0.75-1.42, p=0.83; OR (TT vs. CC/CT) =1.13, 95% CI 0.86-1.50, p=0.37; OR (TT/CT vs. CC) =1.22, 95% CI 0.88-1.68, p=0.24).
|
25007377 |
2014 |
|
rs3087243
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CTLA-4 CT60 (rs3087243) polymorphism and autoimmune thyroid diseases susceptibility: a comprehensive meta-analysis.
|
24697361 |
2014 |
|
rs4704397
|
|
|
0.010 |
GeneticVariation |
BEFREE |
From the Tromsø Study, 8938 subjects without thyroid disease or thyroid medication were successfully genotyped for rs4704397.
|
23941514 |
2014 |
|
rs4522865
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped 3 single nucleotide polymorphisms (SNPs) rs10516487, rs3733197 and rs4522865 of BANK1 gene in 667 patients with autoimmune thyroid diseases (417 with Graves' disease and 250 with Hashimoto's thyroiditis) and 301 healthy controls.
|
24127308 |
2013 |