Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5186
rs5186
0.030 GeneticVariation BEFREE Among individuals with essential hypertension certain relationships were documented between rs5182 and rs5186 polymorphisms of AGTR1 gene and rs1799998 polymorphism of CYP11B2 gene on one hand and the volume of carotid bodies on one other. 29627490

2018

dbSNP: rs5186
rs5186
0.030 GeneticVariation BEFREE Essential hypertension patients were genotyped for 11 polymorphisms of essential hypertension susceptibility genes including ADD1 (rs4961), GNB3 (rs5443, rs16932941), NOS3 (rs1799983, rs2070744), ACE (rs5186), AGTR1 (rs5186), AGT (rs699, rs4762), MR (rs5534), and TGFB1 (rs1800471). 26335431

2015

dbSNP: rs5186
rs5186
0.030 GeneticVariation BEFREE The present study is about a particular genetic polymorphism (A1166C), gene expression and protein expression of the angiotensin II type I receptor (AT1R) (SNP ID: rs5186) and its association with essential hypertension in a Northern Indian population. 24992666

2014

dbSNP: rs5182
rs5182
0.020 GeneticVariation BEFREE Among individuals with essential hypertension certain relationships were documented between rs5182 and rs5186 polymorphisms of AGTR1 gene and rs1799998 polymorphism of CYP11B2 gene on one hand and the volume of carotid bodies on one other. 29627490

2018

dbSNP: rs5182
rs5182
0.020 GeneticVariation BEFREE In a preliminary study we found no association between the distribution of the C/T573 polymorphic site and cardiovascular disease, such as essential hypertension (n = 20) coronary artery disease (n = 16) hypertrophic cardiomyopathy (n = 12) or dilated cardiomyopathy (n = 21). 7713099

1994

dbSNP: rs2638360
rs2638360
0.010 GeneticVariation BEFREE Meta-analysis revealed that C allele of rs2638360 could significantly increase the risk of essential hypertension. 25628312

2015

dbSNP: rs387967
rs387967
0.010 GeneticVariation BEFREE Our findings suggest that rs387967 is associated with the susceptibility to essential hypertension in a Yi population and the tendency was replicated in systolic blood pressure and diastolic blood pressure detection. 25628312

2015

dbSNP: rs12695895
rs12695895
0.010 GeneticVariation BEFREE The present results indicate that rs12695895 might be a genetic marker for EH and Hap4 (AGGACTT) was associated with hypertension in Han Chinese population. 19833117

2010

dbSNP: rs911154679
rs911154679
0.010 GeneticVariation BEFREE Constitutively activated GRK4 gene variants (R65L, A142V, and A486V), by themselves or by their interaction with other genes involved in blood pressure regulation, are associated with essential hypertension and/or salt-sensitive hypertension in several ethnic groups. 20153824

2010

dbSNP: rs777986489
rs777986489
0.010 GeneticVariation BEFREE Both newly detected TSC C1784T and ADRB3 T727C are gene polymorphisms susceptible to the antihypertensive effect of TZDs in patients with EHT. 15824464

2004