Gene: FGFR2 ×
Source: INFERRED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519045
rs1057519045
FGFR2
G 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs1057519795
rs1057519795
FGFR2
C 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs1057519796
rs1057519796
FGFR2
T 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs1057519797
rs1057519797
FGFR2
T 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs1057519798
rs1057519798
FGFR2
C 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs1057519799
rs1057519799
FGFR2
G 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs1057519799
rs1057519799
FGFR2
A 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs1057519799
rs1057519799
FGFR2
T 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs1057519800
rs1057519800
FGFR2
G 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs1057519800
rs1057519800
FGFR2
A 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs1057519800
rs1057519800
FGFR2
T 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs121913476
rs121913476
FGFR2
T 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs121913476
rs121913476
FGFR2
C 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs121918506
rs121918506
FGFR2
C 0.700 GeneticVariation CLINVAR The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. 23908597

2013
dbSNP: rs121913476
rs121913476
FGFR2
T 0.700 GeneticVariation CLINVAR Ponatinib (AP24534), a multitargeted pan-FGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models. 22238366

2012
dbSNP: rs121913476
rs121913476
FGFR2
C 0.700 GeneticVariation CLINVAR FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitor. 23002168

2012
dbSNP: rs121913476
rs121913476
FGFR2
C 0.700 GeneticVariation CLINVAR Ponatinib (AP24534), a multitargeted pan-FGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models. 22238366

2012
dbSNP: rs121913476
rs121913476
FGFR2
T 0.700 GeneticVariation CLINVAR FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitor. 23002168

2012
dbSNP: rs79184941
rs79184941
FGFR2
C 0.700 GeneticVariation CLINVAR Ponatinib (AP24534), a multitargeted pan-FGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models. 22238366

2012
dbSNP: rs79184941
rs79184941
FGFR2
C 0.700 GeneticVariation CLINVAR FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitor. 23002168

2012
dbSNP: rs121913476
rs121913476
FGFR2
T 0.700 GeneticVariation CLINVAR Drug-sensitive FGFR2 mutations in endometrial carcinoma. 18552176

2008
dbSNP: rs121913476
rs121913476
FGFR2
C 0.700 GeneticVariation CLINVAR Drug-sensitive FGFR2 mutations in endometrial carcinoma. 18552176

2008
dbSNP: rs79184941
rs79184941
FGFR2
C 0.700 GeneticVariation CLINVAR Drug-sensitive FGFR2 mutations in endometrial carcinoma. 18552176

2008