Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs63749877
rs63749877
GRN
C 0.700 CausalMutation CLINVAR

dbSNP: rs63751085
rs63751085
GRN
C 0.700 CausalMutation CLINVAR

dbSNP: rs143624519
rs143624519
MAPT
0.010 GeneticVariation BEFREE Rare risk variants, TREM2 R47H and MAPT A152T, were associated with a three- to seven-fold increase in risk for PPA. 30599136

2019
dbSNP: rs75932628
rs75932628
TREM2 ; LOC105375056
0.010 GeneticVariation BEFREE Rare risk variants, TREM2 R47H and MAPT A152T, were associated with a three- to seven-fold increase in risk for PPA. 30599136

2019
dbSNP: rs764232836
rs764232836
GRN
0.010 GeneticVariation BEFREE Rare risk variants, TREM2 R47H and MAPT A152T, were associated with a three- to seven-fold increase in risk for PPA. 30599136

2019
dbSNP: rs63750512
rs63750512
MAPT
0.010 GeneticVariation BEFREE One of the FTDP-17 patients with p.G389R mutation presented at age 24 with agrammatic variant of primary progressive aphasia, and subsequently behavioral dysfunction. 27529406

2017
dbSNP: rs63750301
rs63750301
PSEN1
0.010 GeneticVariation BEFREE We report clinical, neuropsychological, and neuroimaging data in the case of a 47-year-old woman presenting with non-fluent PPA due to a genetically confirmed pathogenic Presenilin 1 P264L mutation. 23579325

2013
dbSNP: rs1064725
rs1064725
APOC1
0.010 GeneticVariation BEFREE LD (r2 = 0.35) between TOMM40 (rs2075650) and APOC1 (rs1064725) was observed in PPA, but not in controls and in bvFTD. 22710912

2012
dbSNP: rs157590
rs157590
TOMM40
0.010 GeneticVariation BEFREE Inside this region of 16.3 kb, LD (r2 = 0.14) between TOMM40 (rs157590) and APOE (rs429358) was observed in PPA, but not in bvFTD and in controls. 22710912

2012
dbSNP: rs2075650
rs2075650
TOMM40
0.010 GeneticVariation BEFREE Inside this region of 26.9 kb, LD (r2 ≥ 0.50) between TOMM40 (rs2075650) and APOE (rs429358) was observed in bvFTD and in controls, but not in PPA. 22710912

2012
dbSNP: rs429358
rs429358
APOE
0.010 GeneticVariation BEFREE Inside this region of 26.9 kb, LD (r2 ≥ 0.50) between TOMM40 (rs2075650) and APOE (rs429358) was observed in bvFTD and in controls, but not in PPA. 22710912

2012