DisGeNET - a database of gene-disease associations

Bilirubin measurement, C0344395

Gene: UGT1A1 ×

Source: GWASDB ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs3755319

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

23642732

2013

dbSNP:

rs3755319

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

23371916

2013

dbSNP:

rs4148323

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

23371916

2013

dbSNP:

rs4148325

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

23642732

2013

dbSNP:

rs6742078

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

23642732

2013

dbSNP:

rs6742078

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

23371916

2013

dbSNP:

rs887829

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

23371916

2013

dbSNP:

rs887829

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

23642732

2013

dbSNP:

rs3755319

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

22085899

2012

dbSNP:

rs4148324

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

22085899

2012

dbSNP:

rs4148325

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

22085899

2012

dbSNP:

rs6742078

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

22085899

2012

dbSNP:

rs887829

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

Taking advantage of the lower LD and shorter haplotypes in African-ancestry populations, we identified rs887829 as a more refined proxy for the causative variant influencing bilirubin levels.

22085899

2012

dbSNP:

rs929596

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

22085899

2012

dbSNP:

rs4148325

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

21646302

2011

dbSNP:

rs28946889

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

Genome-wide association meta-analysis for total serum bilirubin levels.

19414484

2009

dbSNP:

rs3755319

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

Genome-wide association meta-analysis for total serum bilirubin levels.

19414484

2009

dbSNP:

rs3755319

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

19419973

2009

dbSNP:

rs6431630

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

Genome-wide association meta-analysis for total serum bilirubin levels.

19414484

2009

dbSNP:

rs6742078

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

Genome-wide association meta-analysis for total serum bilirubin levels.

19414484

2009

dbSNP:

rs8330

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3 ; MROH2A

0.800

GeneticVariation

GWASDB

Genome-wide association meta-analysis for total serum bilirubin levels.

19414484

2009

dbSNP:

rs887829

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.800

GeneticVariation

GWASDB

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

19419973

2009

dbSNP:

rs6723506

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.700

GeneticVariation

GWASDB

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

23371916

2013

dbSNP:

rs28900396

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.700

GeneticVariation

GWASDB

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

22085899

2012

dbSNP:

rs4148326

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

0.700

GeneticVariation

GWASDB

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

22085899

2012