|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The OPRM1 A118G polymorphism may help predict individuals' response to an</span>algesia and achieve satisfactory cancer pain control.
|
30028366 |
2019 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There was no significant difference in duration of epidural fentanyl analgesia for the three SNVs (161±68 and 143±51 min for wild type and allele carriers of the 118A>G SNV respectively [P=0.08]).
|
29756748 |
2018 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of this study was therefore to address the interaction between the single nucleotide polymorphisms opioid receptor mu 1 (OPRM1) rs1799971 and catechol-O-methyltransferase (COMT) rs4680 on placebo analgesia.
|
30130297 |
2018 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Assays of plasma concentrations of morphine and metabolites (morphine 3-glucuronide and morphine 6-glucuronide) were performed and common polymorphisms in four candidate genes [OPRM1 A118G rs1799971; P-glycoprotein (ABCB1) T3435C (rs1045642) and G2677T/A (rs2032582); COMT Val 158 Met (rs4680)] were analysed.Morphine was titrated by staff in the postanaesthesia care unit (PACU) and in the ward patient-controlled intravenous analgesia was used for 24 h.
|
29474345 |
2018 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This systematic review reveals that CYP2D6, OPRM1 A118G, UGT2B7 C802T and ABCB1 G2677AT may contribute to postpartum analgesia or adverse events.
|
26652709 |
2016 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To further understand the human implications of genetic variation within the opioid system in pain and opioid-mediated placebo responses, we investigated the association between the functional single-nucleotide polymorphism (SNP) in the μ-opioid receptor gene (OPRM1), A118G, and psychophysical responses, personality traits, and neurotransmitter systems (dopamine (DA), opioid) related to pain and placebo analgesia.
|
25308352 |
2015 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The 118A>G variant was associated significantly with the amount of oxycodone requested for adequate analgesia (P = .003, β = .016).
|
25239082 |
2014 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study aimed to investigate the effect of cytochrome P450 3A4 (CYP3A4)*18B polymorphisms and the interaction of the µ opioid receptor gene (OPRM1) A118G and CYP3A4*18B polymorphisms on postoperative fentanyl analgesia in Chinese Han patients undergoing radical gastrectomy.
|
23313934 |
2013 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The time-course for pruritus exactly paralleled the time-course for analgesia and was affected by hospital (P=0.006) and by ethnic group (P=0.03), but not by A118G.
|
23592691 |
2013 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The OPRM1 A118G polymorphism may help predict individuals' response to epidural labor analgesia and so optimize postoperative pain control.
|
23909491 |
2013 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Modeling the influence of the A118G polymorphism in the OPRM1 gene and of noxious stimulation on the synergistic relation between propofol and remifentanil: sedation and analgesia in endoscopic procedures.
|
23503369 |
2013 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The A118G single-nucleotide polymorphism of human μ-opioid receptor gene and use of labor analgesia.
|
22527985 |
2012 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Study of the OPRM1 A118G genetic polymorphism associated with postoperative nausea and vomiting induced by fentanyl intravenous analgesia.
|
21150856 |
2011 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The recessive G allele in the A118G polymorphism may have protective effects against significant pruritus after epidural morphine for post-cesarean analgesia.
|
21039348 |
2010 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association of human micro-opioid receptor gene polymorphism A118G with fentanyl analgesia consumption in Chinese gynaecological patients.
|
20003118 |
2010 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The mu-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers.
|
16906017 |
2006 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association of mu-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty.
|
16879459 |
2006 |
|
rs1799971
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy.
|
16871067 |
2006 |
|
rs4680
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The COMT gene polymorphism was associated with labor anxiety and analgesia among pregnant women, and the Val158Met mutation in the <i>COMT</i> gene could lead to worse labor anxiety and less-effective labor analgesia in pregnant women.
|
30881091 |
2019 |
|
rs4680
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Assays of plasma concentrations of morphine and metabolites (morphine 3-glucuronide and morphine 6-glucuronide) were performed and common polymorphisms in four candidate genes [OPRM1 A118G rs1799971; P-glycoprotein (ABCB1) T3435C (rs1045642) and G2677T/A (rs2032582); COMT Val 158 Met (rs4680)] were analysed.Morphine was titrated by staff in the postanaesthesia care unit (PACU) and in the ward patient-controlled intravenous analgesia was used for 24 h.
|
29474345 |
2018 |
|
rs4680
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Assays of plasma concentrations of morphine and metabolites (morphine 3-glucuronide and morphine 6-glucuronide) were performed and common polymorphisms in four candidate genes [OPRM1 A118G rs1799971; P-glycoprotein (ABCB1) T3435C (rs1045642) and G2677T/A (rs2032582); COMT Val 158 Met (rs4680)] were analysed.Morphine was titrated by staff in the postanaesthesia care unit (PACU) and in the ward patient-controlled intravenous analgesia was used for 24 h.
|
29474345 |
2018 |
|
rs4680
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Influence of catechol-O-methyltransferase Val158Met on fear of pain and placebo analgesia.
|
28968343 |
2018 |
|
rs4680
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The aim of this study was therefore to address the interaction between the single nucleotide polymorphisms opioid receptor mu 1 (OPRM1) rs1799971 and catechol-O-methyltransferase (COMT) rs4680 on placebo analgesia.
|
30130297 |
2018 |
|
rs4680
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Statistically significant associations were found between COMT rs4633 and rs4680 genotypes and the amount of morphine self-administered through a patient-controlled analgesia pump.
|
25963335 |
2016 |
|
rs4680
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The COMT V158M variant has been associated with decreased morphine requirements for analgesia.
|
18370847 |
2008 |