Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4994
rs4994
ADRB3
0.050 GeneticVariation BEFREE In pooled analysis, the rs4994 polymorphism of the ADRB3 gene was associated with overactive bladder (odds ratio [OR], 2.5; 95% confidence interval [CI], 1.7-3.6; n = 419). 25111588

2015
dbSNP: rs4994
rs4994
ADRB3
0.050 GeneticVariation BEFREE These results also demonstrated that the Trp64Arg polymorphism in the β3-AR gene is involved in the pathogenesis of OAB. 25867395

2015
dbSNP: rs4994
rs4994
ADRB3
0.050 GeneticVariation BEFREE As the presence of a Trp64Arg polymorphism of the gene encoding the β(3)-adrenoceptor (B3AR) has been linked to the presence of overactive bladder, we investigated whether additional polymorphisms are detectable in this gene and explore their relationships parameters related to lower urinary tract function. 22972489

2013
dbSNP: rs4994
rs4994
ADRB3
0.050 GeneticVariation BEFREE The Trp 64 Arg polymorphism was associated with OAB syndrome in the Brazilian population. 21529759

2011
dbSNP: rs4994
rs4994
ADRB3
0.050 GeneticVariation BEFREE The association between the tryptophan 64 arginine polymorphism in the beta(3)-AR gene and idiopathic OAB is discussed. 17600372

2007
dbSNP: rs1800896
rs1800896
IL10 ; IL19
0.010 GeneticVariation BEFREE However, allele A of rs1800896 (1082bp upstream) was associated with protection against neurological impairment, specifically overactive bladder (OR=0.447, 95% CI 0.28-0.70, p=0.001). 31166487

2019
dbSNP: rs1325243071
rs1325243071
KLK3
0.010 GeneticVariation BEFREE As the presence of a Trp64Arg polymorphism of the gene encoding the β(3)-adrenoceptor (B3AR) has been linked to the presence of overactive bladder, we investigated whether additional polymorphisms are detectable in this gene and explore their relationships parameters related to lower urinary tract function. 22972489

2013