Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1217691063
rs1217691063
MTHFR
0.010 GeneticVariation BEFREE Presence of the methylenetetrahydrofolate reductase gene polymorphism MTHFR C677T in molar tissue but not maternal blood predicts failure of methotrexate treatment for low-risk gestational trophoblastic neoplasia. 27840191

2017
dbSNP: rs1801131
rs1801131
MTHFR
0.010 GeneticVariation BEFREE MTHFR C677T (rs1801133) and A1298C (rs1801131) were genotyped using high-resolution melting assays in 62 Japanese low-risk GTN patients and in 52 antecedent molar tissues. 27840191

2017
dbSNP: rs1801133
rs1801133
MTHFR
0.010 GeneticVariation BEFREE MTHFR C677T (rs1801133) and A1298C (rs1801131) were genotyped using high-resolution melting assays in 62 Japanese low-risk GTN patients and in 52 antecedent molar tissues. 27840191

2017
dbSNP: rs2228230
rs2228230
PDGFRA
0.010 GeneticVariation BEFREE Genetically, the tumor showed a silent mutation in exon 18 of the PDGFRA gene at codon 824 GTC > GTT (V824V) [rs2228230]. 22009637

2012
dbSNP: rs121913529
rs121913529
KRAS
0.010 GeneticVariation BEFREE With the sensor probe designed for the GAT (G12D) mutant in codon 12 of the K-ras gene, the real-time PCR method also detected the GTT (G12V) mutant. 14718395

2004
dbSNP: rs121913530
rs121913530
KRAS
0.010 GeneticVariation BEFREE In contrast, a specific sensor probe for the TGT (G12C) mutant detected GAT (G12D), AGT (G12S), and GTT (G12V) mutants in addition to the TGT mutant. 14718395

2004
dbSNP: rs28934608
rs28934608
F11
0.010 GeneticVariation BEFREE DNA sequence analysis confirmed three novel mutations; a CGC --> TGC (Arg308Cys) mutation in exon 9, a GCT-->GTT (Ala412Val) mutation in exon 11 and an AGC --> AGA (Ser576Arg) mutation in exon 15. 10606881

1999