Gene: FLT3 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519766
rs1057519766
FLT3
0.010 GeneticVariation BEFREE Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia. 23878140

2013
dbSNP: rs121913488
rs121913488
FLT3
0.010 GeneticVariation BEFREE The antileukemic activity of sorafenib was investigated in isogenic murine Ba/F3 AML cell lines that expressed mutant (ITD, D835G, and D835Y) or wild-type human FLT3, in primary human AML cells, and in a mouse leukemia xenograft model. 18230792

2008
dbSNP: rs35602083
rs35602083
FLT3
0.010 GeneticVariation BEFREE Our data suggest that the FLT3 D324N variant might be associated with a predisposition to different subtypes of leukemia. 16320249

2006