Gene: SDHB ×
Source: CURATED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR Tumour risks and genotype-phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD. 29386252

2018
dbSNP: rs74315366
rs74315366
SDHB
A 0.700 CausalMutation CLINVAR A Duodenal SDH-Deficient Gastrointestinal Stromal Tumor in a Patient With a Germline SDHB Mutation. 28324028

2017
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR The Human Gene Mutation Database: towards a comprehensive repository of inherited mutation data for medical research, genetic diagnosis and next-generation sequencing studies. 28349240

2017
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR SDHB-related pheochromocytoma and paraganglioma penetrance and genotype-phenotype correlations. 28374168

2017
dbSNP: rs772551056
rs772551056
SDHB
T 0.700 GeneticVariation CLINVAR SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery. 26719882

2016
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR Carney triad can be (rarely) associated with germline succinate dehydrogenase defects. 26173966

2016
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 GeneticVariation CLINVAR SDH Subunit Mutation Status in Saliva: Genetic Testing in Patients with Pheochromocytoma. 26916530

2016
dbSNP: rs74315366
rs74315366
SDHB
A 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs772551056
rs772551056
SDHB
T 0.700 GeneticVariation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR Association of urinary bladder paragangliomas with germline mutations in the SDHB and VHL genes. 25683602

2015
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR Lack of utility of SDHB mutation testing in adrenergic metastatic phaeochromocytoma. 25371406

2015
dbSNP: rs74315366
rs74315366
SDHB
A 0.700 CausalMutation CLINVAR Integrative genetic characterization and phenotype correlations in pheochromocytoma and paraganglioma tumours. 24466223

2014
dbSNP: rs74315366
rs74315366
SDHB
A 0.700 CausalMutation CLINVAR Clinical exome sequencing for genetic identification of rare Mendelian disorders. 25326637

2014
dbSNP: rs751000085
rs751000085
SDHB
A 0.700 CausalMutation CLINVAR Pheochromocytoma and paraganglioma syndromes: genetics and management update. 24523625

2014
dbSNP: rs772551056
rs772551056
SDHB
T 0.700 GeneticVariation CLINVAR Clinicopathological study of SDHB mutation-related pheochromocytoma and sympathetic paraganglioma. 24659481

2014
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation. 23282968

2013
dbSNP: rs397516836
rs397516836
SDHB
T 0.700 GeneticVariation CLINVAR Pheochromocytoma and paraganglioma: understanding the complexities of the genetic background. 22429592

2012
dbSNP: rs397516836
rs397516836
SDHB
T 0.700 GeneticVariation CLINVAR Screening of mutations in genes that predispose to hereditary paragangliomas and pheochromocytomas. 22517554

2012
dbSNP: rs727504457
rs727504457
SDHB
G 0.700 GeneticVariation CLINVAR A decade (2001-2010) of genetic testing for pheochromocytoma and paraganglioma. 22517557

2012
dbSNP: rs74315366
rs74315366
SDHB
A 0.700 CausalMutation CLINVAR Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer. 23083876

2012
dbSNP: rs74315366
rs74315366
SDHB
A 0.700 CausalMutation CLINVAR High prevalence of founder mutations of the succinate dehydrogenase genes in the Netherlands. 21348866

2012
dbSNP: rs772551056
rs772551056
SDHB
T 0.700 GeneticVariation CLINVAR Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer. 23083876

2012
dbSNP: rs397516836
rs397516836
SDHB
T 0.700 GeneticVariation CLINVAR Genetics and clinical characteristics of hereditary pheochromocytomas and paragangliomas. 22041710

2011
dbSNP: rs74315366
rs74315366
SDHB
A 0.700 CausalMutation CLINVAR [The mutations of germline succinate dehydrogrnase subunit B (SDHB) in sporadic paragangliomas]. 21909610

2011