In humans, we tested the genetic association of disease severity in influenza A/H1N1pdm09-infected patients with three potentially functional <i>PIK3CG</i> single-nucleotide polymorphisms (SNPs), rs1129293, rs17847825, and rs2230460.
We observed that SNPs rs17847825 and rs2230460 (A and T alleles, respectively) were significantly associated with protection from severe disease using the recessive model in patients infected with influenza A</span>(H1N1)pdm09.
We observed that SNPs rs17847825 and rs2230460 (A and T alleles, respectively) were significantly associated with protection from severe disease using the recessive model in patients infected with influenza A(H1N1)pdm09.