|
rs924607
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Lack of association of the CEP72 rs924607 TT genotype with vincristine-related peripheral neuropathy during the early phase of pediatric acute lymphoblastic leukemia treatment in a Spanish population.
|
26618658 |
2016 |
|
rs924607
|
|
T |
0.710 |
GeneticVariation |
GWASCAT |
Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia.
|
25710658 |
2015 |
|
rs1858826
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide meta-analyses identifies novel taxane-induced peripheral neuropathy-associated loci.
|
29278617 |
2018 |
|
rs12786200
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia.
|
25710658 |
2015 |
|
rs17032980
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia.
|
25710658 |
2015 |
|
rs4463516
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia.
|
25710658 |
2015 |
|
rs7818688
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia.
|
25710658 |
2015 |
|
rs76992529
|
|
|
0.020 |
GeneticVariation |
BEFREE |
On multivariate analysis, age at diagnosis (risk ratio, 15.65; p < 0.0001), Thr60Ala mutation (risk ratio, 1.52; p = 0.04), Val122Ile mutation (risk ratio, 2.83; p = 0.003), peripheral neuropathy (risk ratio, 1.69; p = 0.013) and weight loss (risk ratio, 1.81; p = 0.002) were risk factors for death.
|
26017327 |
2015 |
|
rs76992529
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The patient and some members of his family also had mild peripheral neuropathy suggesting a regional phenotypic heterogeneity of European Caucasian TTR p.Val122Ile.
|
22449240 |
2012 |
|
rs387907272
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This retrospective observational analysis of IgM paraprotein-associated PN identified five patients with small pathological MYD88 L265P and CD20-positive B-cell clones in their bone marrow using multi-parametric flow cytometry, who have shown durable neurological response to rituximab.
|
31588566 |
2020 |
|
rs113993956
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The R941L mutation in MYH14 disrupts mitochondrial fission and associates with peripheral neuropathy.
|
31231018 |
2019 |
|
rs1279417718
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Related adults heterozygous for YARS p.Pro167Thr showed no evidence of peripheral neuropathy on electromyography, in contrast to previous reports for other YARS variants.
|
30304524 |
2019 |
|
rs281865128
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Sixty-three members of a large CMT 1B kindred were assessed for signs of peripheral neuropathy and cranial neuropathies then tested for the G163R mutation in the myelin protein zero (MPZ) gene.
|
30920665 |
2019 |
|
rs3025039
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conclude that the VEGF+936 C/T (rs3025039) gene polymorphisms are related to peripheral neuropathy in Mexican DM2 patients, with the heterozygous genotype potentially conferring a protective effect.
|
31499478 |
2019 |
|
rs12521798
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified 4 new promising loci for bortezomib-induced PNP at 4q34.3 (rs6552496), 5q14.1 (rs12521798), 16q23.3 (rs8060632), and 18q21.2 (rs17748074).
|
28317148 |
2018 |
|
rs17748074
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified 4 new promising loci for bortezomib-induced PNP at 4q34.3 (rs6552496), 5q14.1 (rs12521798), 16q23.3 (rs8060632), and 18q21.2 (rs17748074).
|
28317148 |
2018 |
|
rs3750898
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Asp317His in DCLRE1A was most associated with peripheral neuropathy (OR 1.3, 95% CI 1.1-1.6, P = 0.003).
|
30114658 |
2018 |
|
rs6265
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These observations suggest that BDNF Val66met-SNP has no detectable effect on the peripheral neuropathy that is induced by paclitaxel.
|
30550003 |
2018 |
|
rs6552496
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified 4 new promising loci for bortezomib-induced PNP at 4q34.3 (rs6552496), 5q14.1 (rs12521798), 16q23.3 (rs8060632), and 18q21.2 (rs17748074).
|
28317148 |
2018 |
|
rs759834365
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These observations suggest that BDNF Val66met-SNP has no detectable effect on the peripheral neuropathy that is induced by paclitaxel.
|
30550003 |
2018 |
|
rs8060632
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified 4 new promising loci for bortezomib-induced PNP at 4q34.3 (rs6552496), 5q14.1 (rs12521798), 16q23.3 (rs8060632), and 18q21.2 (rs17748074).
|
28317148 |
2018 |
|
rs6746030
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SCN9A rs6746030 was associated with protection for severe oxaliplatin-induced peripheral neuropathy.
|
28103821 |
2017 |
|
rs80356711
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We describe the neurological, cognitive, neuroimaging, and electrophysiological features of a 31-year-old man presenting with an orbitofrontal syndrome, gastrointestinal symptoms, and peripheral neuropathy associated with PRNP Q160X nonsense mutation, with symptom onset at age 27.
|
27716661 |
2017 |
|
rs1555937122
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicated that the Leu89Pro substitution in the second transmembrane domain of CX32 disrupts the trafficking of the protein, inhibiting the assembly of CX32 gap junctions, which in turn may result in peripheral neuropathy.
|
27367520 |
2016 |
|
rs1801198
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The TCN2 776C→G polymorphism is associated with increased odds of peripheral neuropathy in the elderly, even with a normal vitamin B-12 status, especially if their folate intake is >2 times the Recommended Dietary Allowance.
|
27733392 |
2016 |