MIR301B, microRNA 301b, 100126318

N. diseases: 34; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027055
Disease: Myocardial Reperfusion Injury
Myocardial Reperfusion Injury
0.300 Biomarker phenotype CTD_human Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti-angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ-tocotrienol. 22050707 2012
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse
0.300 Biomarker disease CTD_human Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. 20643829 2010
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders
0.300 Biomarker group CTD_human Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. 20643829 2010
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.300 Biomarker disease CTD_human Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. 20643829 2010
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 AlteredExpression group BEFREE Interestingly, GC tissues from patients with tumor size ≥ 5 cm and advanced tumor stages showed obvious higher levels of miR-301b-3p compared to matched controls. 31585814 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE At last, upregulated lncRNA MBNL1-AS1 or depleted miR-301b-3p suppressed the xenograft tumor formation in vivo. 31113460 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE Furthermore, miR-301b-3p knockdown suppressed tumour growth of HCC in mice. 31207037 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 Biomarker phenotype BEFREE Moreover, miR-301b-3p could down-regulate LRP1B by interacting with LRP1B, which acted to promote the proliferation, migration and invasion abilities of prostate cancer cells in addition to tumor growth in vivo. 31442444 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 Biomarker phenotype BEFREE Transwell assay validated the oncogenic effect of miR-301b-3p on migration and invasion of HGS-OvCa cells. 30834603 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 Biomarker phenotype BEFREE In conclusion, it was found that <i>LUCAT1</i> was activated by <i>STAT3</i> and promoted cell proliferation, migration, and invasion in HB through modulation of the <i>miR-301b/STAT3</i> axis. 30479162 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 Biomarker phenotype BEFREE Our study indicates that the inhibition of miR-301b represses the proliferation and invasion of glioma cells by up-regulating GPC5 expression. 30951720 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 Biomarker phenotype BEFREE This study is the first to report that BHLHE40/41 and the MIR301B-MIR130B cluster suppressed each other to regulate EMT and invasion of EC cells. 31384392 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE Intratumorally administration of miR-301b angomir enhances the inhibitory effect of ISL on tumor growth in vivo. 30081934 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 Biomarker phenotype BEFREE We investigated the role of miR-301b in the modulation of the proliferation, migration, and invasion of bladder cancer (BLCA) cells. 28521108 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 AlteredExpression group BEFREE PDAC tumors expressing high levels of MIF displayed elevated levels of miR-301b and reduced levels of NR3C2. 27197190 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 AlteredExpression group BEFREE In the xenograft model, overexpression of miR-301b promoted tumour growth. 27352910 2016
Malignant neoplasm of urinary bladder
0.030 AlteredExpression disease BEFREE q-RT-PCR was performed to examine the expression of miR-130b-3p, miR-301b-3p and USP13 in BC tissue samples. 31200745 2019
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.030 AlteredExpression disease BEFREE q-RT-PCR was performed to examine the expression of miR-130b-3p, miR-301b-3p and USP13 in BC tissue samples. 31200745 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.030 Biomarker group BEFREE Increasing evidence suggests that miR-301b-3p functions as a driver in various types of human cancer. 31207037 2019
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.030 AlteredExpression disease BEFREE q-RT-PCR was performed to examine the expression of miR-130b-3p, miR-301b-3p and USP13 in BC tissue samples. 31200745 2019
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.030 Biomarker group BEFREE Increasing evidence suggests that miR-301b-3p functions as a driver in various types of human cancer. 31207037 2019
Malignant neoplasm of urinary bladder
0.030 AlteredExpression disease BEFREE Our results showed that miR-301b was up-regulated while EGR1 was down-regulated in BLCA tissues compared with adjacent normal tissues. 28521108 2017
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.030 AlteredExpression disease BEFREE Our results showed that miR-301b was up-regulated while EGR1 was down-regulated in BLCA tissues compared with adjacent normal tissues. 28521108 2017
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.030 AlteredExpression disease BEFREE Our results showed that miR-301b was up-regulated while EGR1 was down-regulated in BLCA tissues compared with adjacent normal tissues. 28521108 2017
Malignant neoplasm of urinary bladder
0.030 AlteredExpression disease BEFREE We focused on the miR-130 family (miR-130b, miR-301a, and miR-301b) that was significantly upregulated in bladder cancer specimens than that of the normal urothelial specimens. 26837847 2016