Disease: HIV-1 infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.100 AlteredExpression disease BEFREE MARCH2 inhibits the production and infection of HIV-1 through ligase activity-dependent envelope protein degradation and/or intracellular retention, a mechanism shared by MARCH8 that also leads to the inhibition of HIV-1 infection. 29573664 2018
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.100 AlteredExpression disease BEFREE Antibodies bound to human immunodeficiency virus type 1 (HIV-1) envelope protein expressed by infected cells mobilize antibody-dependent cellular cytotoxicity (ADCC) to eliminate the HIV-1-infected cells and thereby suppress HIV-1 infection and delay disease progression. 28794022 2017
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.100 Biomarker disease BEFREE We evaluated the risk factors for intrafamilial transmission of HIV-1 infection through qualitative epidemiology following pol and env gene sequencing and phylogenetic analysis. 22918554 2013
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.100 Biomarker disease BEFREE For example, the evolution of Env during the course of HIV-1 infection increases the efficiency of Env-CCR5 interactions, which consequently increases Env-mediated fusogenicity and decreases sensitivity to entry inhibitors. 17073614 2006
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.100 Biomarker disease BEFREE Efficient human immunodeficiency virus (HIV)-1 infection depends on multiple interactions between the viral gp41/gp120 envelope (Env) proteins and cell surface receptors. 16148047 2005
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.100 GeneticVariation disease BEFREE We analysed three host response and viral characteristics were associated with recent HIV-1 infection: rapidly increasing EIA optical density (OD) values, genetically homogeneous env gene quasispecies, and putative non-syncytium inducing env V3 loop sequences. 11741169 2002
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.100 Biomarker disease BEFREE Infection of macaques with chimeric simian/human immunodeficiency virus (SHIV) expressing the envelope protein of HIV-1 provides a model system for studying HIV-1 infection in humans. 9705259 1998
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.100 Biomarker disease BEFREE According to the rate of depletion of CD4 cell counts, we grouped 12 cases of human immunodeficiency virus type 1 (HIV-1) infection as 6 rapid (21.0 to 33.8 cells per microl per month) and 6 slow (0.9 to 7.9 cells per microl per month) progressors and determined the individual viral quasispecies patterns by sequencing the genome region encoding the V1, V2, and V3 loops of envelope protein. 9188549 1997
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.100 GeneticVariation disease BEFREE To determine HIV-1 genomic RNA and proviral DNA sequences of the third hypervariable region (V3 loop) of the envelope protein in patients with primary HIV-1 infection (PHI), and to compare these sequences with sequences from patients with more advanced HIV-1 infection. 7893436 1995
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.100 Biomarker disease BEFREE HIV-1 infection of a human T-cell line transduced with this vector led to induction of sCD4-KDEL synthesis and a block in transport of the HIV envelope protein to the cell surface. 8464877 1993
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.100 Biomarker disease BEFREE Our data suggest that antibodies against select epitopes of HIV envelope protein gp120 might play an important role in preventing mother-to-child transmission of HIV-1 infection. 2479014 1989