CNR1, cannabinoid receptor 1, 1268

N. diseases: 393; N. variants: 21
Disease: Anhedonia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178417
Disease: Anhedonia
Anhedonia 		0.020 Biomarker disease BEFREE Deficiency of CB1 receptor signaling is associated with anhedonia, anxiety, and persistence of negative memories. 24882055 2014
CUI: C0178417
Disease: Anhedonia
Anhedonia 		0.020 GeneticVariation disease BEFREE To examine whether a synonymous polymorphism, rs1049353, in exon 4 of the gene encoding the human endocannabinoid receptor (CNR1) moderates the effect of self-reported childhood physical abuse on lifetime anhedonia and depression and to replicate this interaction in an independent sample. 22393204 2012