CPA1, carboxypeptidase A1, 1357

N. diseases: 61; N. variants: 2
Disease: Pancreatitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030305
Disease: Pancreatitis
Pancreatitis 		0.020 Biomarker disease BEFREE In 2013, carboxypeptidase A1 (CPA1) was identified as a novel pancreatitis susceptibility gene. 24522117 2014
CUI: C0030305
Disease: Pancreatitis
Pancreatitis 		0.020 GeneticVariation disease BEFREE The mechanism by which CPA1 variants confer increased pancreatitis risk may involve misfolding-induced endoplasmic reticulum stress rather than elevated trypsin activity, as is seen with other genetic risk factors for this disease. 23955596 2013