ADORA2B, adenosine A2b receptor, 136

N. diseases: 66; N. variants: 2
Disease: Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 AlteredExpression group BEFREE Moreover, in in vivo xenograft experiments, chemical and genetic abrogation of ADORA2B activity impaired tumor growth associated with decreased tumor vascularization. 31846065 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 AlteredExpression group BEFREE ADORA2B-expression was significantly correlated with ER (<i>P</i> < 0.01), PgR (<i>P</i> = 0.027), EGFR (<i>P</i> < 0.01), and tumor size (<i>P</i> = 0.037), and was an independent prognostic factor for outcome (<i>P</i> = 0.036). 30349649 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 AlteredExpression group BEFREE Both RNAi silencing and pharmacologic blockade of ADORA2B inhibited filopodia formation and invasive activity of breast cancer cells and correspondingly reduced tumor outgrowth in the lungs. 23483055 2013