AFP, alpha fetoprotein, 174

N. diseases: 392; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019159
Disease: Hepatitis A
Hepatitis A
0.100 Biomarker disease BEFREE Especially, plasma circSMARCA5 presented a high accuracy (AUC = 0.847, 0.706) for detecting HCC with serum AFP below 200 ng/ml from those hepatitis and cirrhosis with AFP below 200 ng/ml. 30716279 2019
CUI: C0019159
Disease: Hepatitis A
Hepatitis A
0.100 Biomarker disease BEFREE AFP-L3, has been proposed to differentiate HCC and hepatitis in elevated AFP cases in Japan for decades, but the utility is limited outside Japan. 30309487 2018
CUI: C0019159
Disease: Hepatitis A
Hepatitis A
0.100 Biomarker disease BEFREE Conclusively, HAS may be misdiagnosed as hepatocellular carcinoma; therefore, it should be considered in the differential diagnosis of multiple hepatic nodules with high AFP and no history of hepatitis, liver fibrosis or cirrhosis. 29034239 2017
CUI: C0019159
Disease: Hepatitis A
Hepatitis A
0.100 Biomarker disease BEFREE Therefore, a rapid, convenient detect kit for AFP is necessary for the hepatitis patients to test AFP at home by themselves. 28670498 2017
CUI: C0019159
Disease: Hepatitis A
Hepatitis A
0.100 AlteredExpression disease BEFREE High-risk patients with tumors > 1 cm with one or two image findings consistent with HCC and tumors < 1 cm with two or more image findings consistent with HCC with persistently increased serum alpha-fetoprotein (AFP) levels above the normal range with underlying inhibited hepatitis activity underwent liver resection. 28049244 2017
CUI: C0019159
Disease: Hepatitis A
Hepatitis A
0.100 Biomarker disease BEFREE Our result demonstrated that common terms in both no-tumor hepatitis/cirrhotic liver tissues and HCC include secreted extracellular region, extracellular region part, extracellular space, signal peptide, signal, disulfide bond, glycosylation site N-linked (GlcNAc...), and glycoprotein, and these terms are less relative to invasion; therefore, we deduced the weaker AFP secreted network in HCC consistent with our number computation. 20532728 2010
CUI: C0019159
Disease: Hepatitis A
Hepatitis A
0.100 Biomarker disease BEFREE Alpha-fetoprotein was greater in patients with hepatitis, and hepatocellular carcinoma was detected in 3.63% of the patients with hepatic cirrhosis. 18553011 2008
CUI: C0019159
Disease: Hepatitis A
Hepatitis A
0.100 AlteredExpression disease BEFREE The patterns of HBsAg and HCV in 100 cases of HCC and their surrounding liver tissues were studied on paraffin-embedded sections with immuno-histochemistry, the histological status was determined by one pathologist and one surgeon simultaneously using the hepatitis activity index (HAI) score, and AFP was detected by radioimmunity. 17465484 2007
CUI: C0019159
Disease: Hepatitis A
Hepatitis A
0.100 AlteredExpression disease BEFREE No relationship was found between the expression of CTA and clinical indicators such as age, sex, tumor size, TNM staging, serum AFP level and infection with hepatitis virus. 16546222 2006
CUI: C0019159
Disease: Hepatitis A
Hepatitis A
0.100 AlteredExpression disease BEFREE Meanwhile, AFP mRNA was markedly expressed in HCC patients compared to the patients with no HCC (LC and hepatitis). 15993394 2005
CUI: C0019159
Disease: Hepatitis A
Hepatitis A
0.100 AlteredExpression disease BEFREE High alpha-fetoprotein level correlates with high stage, early recurrence and poor prognosis of hepatocellular carcinoma: significance of hepatitis virus infection, age, p53 and beta-catenin mutations. 15305374 2004