|
Adult Yolk Sac Tumor
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The AFP levels were elevated in 8 cases of yolk sac tumor.
|
31627179 |
2020 |
|
Adult Yolk Sac Tumor
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
It has been suggested that alpha-fetoprotein (AFP) can be applied as a feasible tumor marker because its level was elevated in >90% of YST.
|
31114774 |
2019 |
|
Adult Yolk Sac Tumor
|
0.100 |
Biomarker
|
disease |
BEFREE |
The current study is a multi-faceted examination of yolk sac tumor-like phenotypes in endometrial tumors, based on an analysis of 3 groups of uterine tumors: Group 1: 9 endometrial tumors that had been classified as yolk sac tumor, or as having a yolk sac tumor component, were assessed with a 35-marker immunohistochemical panel, with the goal of defining their immunophenotypic spectrum; Group 2, comprised of 70 endometrial carcinomas of various histotypes, were analyzed for their expression of SALL4, Glypican-3, and AFP, to assess the specificity of these markers for yolk sac tumors relative to endometrial carcinomas; Group 3, comprised of 626 archived cases of endometrial carcinoma/carcinosarcoma, reviewed to define the frequency of yolk sac tumor-like morphology therein.
|
31375771 |
2019 |
|
Adult Yolk Sac Tumor
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This 18-year-old woman underwent laparoscopic pelvic tumor resection, considered her first surgery, 2 years ago, and pathology revealed YST with initial alpha-fetoprotein (AFP) level measuring >3,000 ng/mL.
|
30992672 |
2019 |
|
Adult Yolk Sac Tumor
|
0.100 |
Biomarker
|
disease |
BEFREE |
Alpha-fetoprotein (AFP) is a useful tumor marker for ovarian germ cell tumors, particularly yolk sac tumor (YST).
|
29933751 |
2018 |
|
Adult Yolk Sac Tumor
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The intestinal-type mucinous glands were immunoreactive for SALL4 (4 cases), AFP (4 cases), glypican 3 (1 case), CDX2 (6 cases), and villin (7 cases), markers that are commonly expressed in YSTs, although the latter 2 markers would be expected to be positive in intestinal-type glands.
|
28582340 |
2018 |
|
Adult Yolk Sac Tumor
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
For germ cell tumors, the mean preoperative serum α-fetoprotein (AFP) level was significantly higher in patients with yolk sac tumor than in those with teratomas (2,078 ng/mL vs 5.7 ng/mL).
|
30324570 |
2018 |
|
Adult Yolk Sac Tumor
|
0.100 |
Biomarker
|
disease |
BEFREE |
Alpha-fetoprotein (AFP) is a well-known tumor marker of hepatic carcinoma and yolk sac tumor.
|
29788728 |
2018 |
|
Adult Yolk Sac Tumor
|
0.100 |
Biomarker
|
disease |
BEFREE |
In all patients, elevation of alpha-fetoprotein indicated a yolk sac tumor component.
|
28306215 |
2017 |
|
Adult Yolk Sac Tumor
|
0.100 |
Biomarker
|
disease |
BEFREE |
This proportion of patients is even lower for those with seminomas or pure embryonal carcinomas as alpha-fetoprotein is predominantly related to yolk sac tumor and human chorionic gonadotropin to choriocarcinoma.
|
24922631 |
2014 |
|
Adult Yolk Sac Tumor
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We analyzed EPCAM expression by quantitative RT-PCR in 48 fresh-frozen GCT specimens of different histology (10 mature teratoma, MT; 6 immature teratoma, IT; 7 dysgerminoma; 6 mixed malignant GCTs; 19 yolk sac tumor, YST) and in the GCT cell lines NCCIT, TE76.T, JAR and 2102Ep, and correlated its expression with AFP and hCG protein levels, histologic differentiation, and clinical follow-up data.
|
22987628 |
2013 |