AGT, angiotensinogen, 183

N. diseases: 146; N. variants: 14
Disease: Heart failure ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018801
Disease: Heart failure
Heart failure 		0.600 Biomarker disease CTD_human We tested the hypothesis that levosimendan, an inodilator that acts through calcium sensitization, opening of ATP-dependent potassium channels and phosphodiesterase III inhibition, improves cardiac function and survival in double transgenic rats harboring human renin and angiotensinogen genes (dTGRs), a model of angiotensin II (Ang II)-induced hypertensive heart failure. 20811386 2010
CUI: C0018801
Disease: Heart failure
Heart failure 		0.600 Biomarker disease CTD_human Angiotensin II and norepinephrine induce programmed cell death (apoptosis) in myocardial cells, thereby contributing to the progression of left ventricular function to heart failure. 12025466 2002
CUI: C0018801
Disease: Heart failure
Heart failure 		0.600 Biomarker disease CTD_human Differential effects of captopril and enalapril on tissue renin-angiotensin systems in experimental heart failure. 1330361 1992