EPHB2, EPH receptor B2, 2048

N. diseases: 649; N. variants: 19
Disease: Ependymoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014474
Disease: Ependymoma
Ependymoma 		0.320 Biomarker disease CTD_human An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes. 26075792 2015
CUI: C0014474
Disease: Ependymoma
Ependymoma 		0.320 Biomarker disease BEFREE We propose that EphB2 mediated ependymoma development is a multifactorial process requiring microenvironment directed receptor activation, resulting in changes in the phosphorylation status of key regulatory proteins, maintenance of a stem-like state and cellular proliferation. 25801123 2015
CUI: C0014474
Disease: Ependymoma
Ependymoma 		0.320 Biomarker disease BEFREE The transcriptome of human supratentorial ependymomas with amplified EPHB2 and deleted INK4A/ARF matched only that of embryonic cerebral Ink4a/Arf(-/-) NSCs. 20639864 2010