EPHB2, EPH receptor B2, 2048

N. diseases: 649; N. variants: 19
Disease: Stage IIB Gallbladder Cancer AJCC v8 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4525301
Disease: Stage IIB Gallbladder Cancer AJCC v8
Stage IIB Gallbladder Cancer AJCC v8 		0.050 Biomarker disease BEFREE Our study identified that SLC25A22 promoted development of GBC activating MAPK/ERK pathway. 30814911 2019
CUI: C4525301
Disease: Stage IIB Gallbladder Cancer AJCC v8
Stage IIB Gallbladder Cancer AJCC v8 		0.050 Biomarker disease BEFREE EMP3, which is regulated by miR-663a, suppresses gallbladder cancer progression via interference with the MAPK/ERK pathway. 29778567 2018
CUI: C4525301
Disease: Stage IIB Gallbladder Cancer AJCC v8
Stage IIB Gallbladder Cancer AJCC v8 		0.050 Biomarker disease BEFREE Therefore, ERK1/2 and p-ERK1/2 seem to be important in the development of GBC and GB-d1, G415 and NOZ cell lines may be used as experimental models for further in vitro and in vivo studies that help to decipher the role of MAPK/ERK pathway in gallbladder carcinogenesis. 28285962 2017
CUI: C4525301
Disease: Stage IIB Gallbladder Cancer AJCC v8
Stage IIB Gallbladder Cancer AJCC v8 		0.050 AlteredExpression disease BEFREE PHB and p-ERK protein expressions were determined in human GBC tissues by immunohistochemistry (IHC). 27084680 2016
CUI: C4525301
Disease: Stage IIB Gallbladder Cancer AJCC v8
Stage IIB Gallbladder Cancer AJCC v8 		0.050 AlteredExpression disease BEFREE ARB blocked A2-induced GBC cell growth and activated ERK. 25663464 2015