F11, coagulation factor XI, 2160

N. diseases: 100; N. variants: 139
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042974
Disease: von Willebrand Disease
von Willebrand Disease
0.030 Biomarker disease BEFREE The following tests were conducted: prothrombin time (<i>n</i> = 125), international normalized ratio (<i>n</i> = 146), activated partial thromboplastin time (<i>n</i> = 119), thrombin time (<i>n</i> = 105), fibrinogen (<i>n</i> = 125), factor (F)II (<i>n</i> = 69), FV (<i>n</i> = 64), FVII (<i>n</i> = 64), FX (<i>n</i> = 67), FVIII (<i>n</i> = 55), FIX (<i>n</i> = 37), FXI (<i>n</i> = 35), and FXIII (<i>n</i> = 20), D-dimer (<i>n</i> = 34), antithrombin (<i>n</i> = 31), anti-Xa activity (<i>n</i> = 30), von Willebrand antigen (<i>n</i> = 25), and von Willebrand activity (VWF:GPIbM; <i>n</i> = 27). 31600807 2019
CUI: C0042974
Disease: von Willebrand Disease
von Willebrand Disease
0.030 AlteredExpression disease BEFREE Cases with isolated prolonged APTT were tested for factors VIII and IX using factor assays This was followed by FXI:C level assessment in cases with normal FVIII and FIX levels. vWD was screened in patients with low FVIII levels. 28388959 2017
CUI: C0042974
Disease: von Willebrand Disease
von Willebrand Disease
0.030 Biomarker disease BEFREE Compared with females with von Willebrand disease or FXI deficiency, females with FIX deficiency were more likely to experience postpartum bleeding (P = 0.008) and anaemia (P = 0.045); and they were less likely to experience menorrhagia (P = 0.065), but the latter did not reach significance. 15357775 2004