F11, coagulation factor XI, 2160

N. diseases: 100; N. variants: 139
Disease: Venous Thromboembolism ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 Biomarker phenotype BEFREE FXIa (factor XIa) induces clot formation, and human congenital FXI deficiency protects against venous thromboembolism and stroke. 31766871 2020
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 Biomarker phenotype BEFREE SUMMARY: Background and objectives Low factor XI activity (FXIa) reduces the risk of venous thromboembolism (VTE), and FXI is regarded as a potential target for anticoagulation. 30784172 2019
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 GeneticVariation phenotype GWASCAT Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism. 31420334 2019
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 GeneticVariation phenotype GWASCAT Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. 31676865 2019
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 GeneticVariation phenotype GWASCAT Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor. 28373160 2017
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 GeneticVariation phenotype GWASCAT Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism. 25772935 2015
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 GeneticVariation phenotype BEFREE We studied prospectively the associations of plasma factor XI and a key F11 genetic variant with incident VTE in whites and African-Americans. 26260105 2015
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 GeneticVariation phenotype BEFREE A nucleotide variant (rs3756008) in the promoter region of the FXI gene was recently reported for association with venous thromboembolism. 24420855 2014
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 GeneticVariation phenotype GWASCAT A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. 23650146 2013
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 GeneticVariation phenotype GWASDB A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. 23650146 2013
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 GeneticVariation phenotype GWASDB A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q. 22672568 2012
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 GeneticVariation phenotype GWASDB Genetics of venous thrombosis: insights from a new genome wide association study. 21980494 2011