SIRT1, sirtuin 1, 23411

N. diseases: 675; N. variants: 21
Disease: Intercritical gout ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1281373
Disease: Intercritical gout
Intercritical gout 		0.010 Biomarker disease BEFREE In the in vitro experiment, SIRT1, autophagy-related genes (beclin-1 and microtubule-associated protein 1 light-chain 3) and key genes involved in the gouty inflammatory pathway, including NF-κB p65, NLR family pyrin domain containing 3 (NLRP3), caspase-1 and IL-1β, were determined in PBMCs lysate or plasma from IG patients exposed to monosodium urate (MSU) crystals with or without resveratrol. 30600470 2019