Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 AlteredExpression group BEFREE High values of the AEG1 protein (linked to metastases) were detected alongside a high expression of BRMS1 (a suppressor of metastases). 30822630 2019
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE Breast cancer metastasis suppressor 1 (BRMS1) is a tumor metastasis suppressor implicated in multiple steps during the metastatic cascade. 30365131 2019
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE Tumor metastasis suppressor factor BRMS1 can regulate the metastasis of breast cancer and other tumors. 30034938 2018
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 AlteredExpression group BEFREE BRMS1 Expression in Surgically Resected Lung Adenocarcinoma Predicts Future Metastases and Is Associated with a Poor Prognosis. 29097253 2018
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE Breast cancer metastasis suppressor 1 (BRMS1) can specifically regulate tumor metastasis in many cancers. 28339067 2017
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE These observations offer fresh insight into the mechanisms through which BRMS1 regulates the development of metastases in NSCLC. 25368381 2015
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE Breast cancer metastasis suppressor 1 (BRMS1) is able to suppress tumor metastasis without affecting primary tumor growth in various cancers. 23643861 2013
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE Loss of BRMS1 expression correlates with tumor progression, and BRMS1 suppresses several steps required for tumor metastasis. 22927944 2012
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE The breast cancer metastasis suppressor 1 (BRMS1) is a member of a family of proteins that actively suppress tumour metastasis. 19401233 2009
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE Coupled with previous reports showing modest effects of BRMS1 on adhesion and invasion, our results indicate that BRMS1 inhibits metastases in multiple organs by blocking several steps in the metastatic cascade. 18276787 2008
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE Suppression of OPN may be one of the possible underlying mechanisms of BRMS1-dependent suppression of tumor metastasis. 17227585 2007
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE These results suggest that at least one of the underlying mechanisms of BRMS1-dependent suppression of tumor metastasis includes inhibition of NF-kappaB activity and subsequent suppression of uPA expression in breast cancer and melanoma cells. 15867352 2005