GH1, growth hormone 1, 2688

N. diseases: 686; N. variants: 27
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 Biomarker disease BEFREE The aim of this article is to report a case of CCF after the endoscopic resection of a growth hormone secreting pituitary microadenoma, and to discuss and review all the cases of CCF secondary to transsphenoidal procedures described in literature. 31712112 2020
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 Biomarker disease BEFREE This article appraises the current evidence regarding growth hormone and testosterone deficiencies in HF and reviews novel findings about the treatment of these conditions in HF. 31079696 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 Biomarker disease BEFREE Combined effects of growth hormone and testosterone replacement treatment in heart failure. 31696666 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 Biomarker disease BEFREE Growth Hormone Therapy in Heart Failure. 30266359 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 Biomarker disease BEFREE Interestingly, GH replacement therapy represents a possible future therapeutic option in CHF. 29153202 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 AlteredExpression disease BEFREE Clinical trials also indicate that in CHF patients with low insulin-like growth factor-1 or low thyroid hormone levels, supplemental treatment with growth hormone or thyroid hormone seems to be cardioprotective; and in CHF patients with volume overload the vasopressin antagonists can relieve the symptoms superior to loop diuretics. 29468912 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 Biomarker disease BEFREE Decreased anabolism because of alterations in the insulin-like growth factor 1 (IGF-1)/growth hormone (GH) axis and increased catabolism induced by proinflammatory cytokines like tumor necrosis factor α (TNF-α) and interleukin 6 (IL-6) have been reported to contribute to muscle wasting in chronic heart failure (CHF). 28695463 2017
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 Biomarker disease BEFREE In this study, we evaluated the effects of GH on soleus muscle and cardiac remodeling in rats with aortic stenosis (AS)-induced HF. 29137319 2017
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 Biomarker disease BEFREE Although mounting evidence supports the concept that growth hormone (GH) deficiency (GHD) affects cardiovascular function, no study has systematically investigated its prevalence and role in a large cohort of chronic heart failure (CHF) patients. 28095492 2017
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 Biomarker disease BEFREE Acromegaly is a pathological condition associated with excess growth hormone (GH) and insulin-like growth factor-I (IGF-I) and a high prevalence of diabetes, hypertension, atherosclerosis, and heart failure; resulting in premature death. 22370764 2012
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 Biomarker disease BEFREE Decreased GH, decreased IGF-I and increased MMP-9 activities may be possible diagnostic markers in RHD for developing heart failure. 16406300 2006
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 AlteredExpression disease BEFREE We hypothesized that local myocardial overexpression of GH could prevent ventricular remodeling and heart failure following myocardial infarction (MI) in rats. 15081312 2004
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 Biomarker disease BEFREE We tested the hypothesis that GH could improve cardiac and renal function in volume overload-induced heart failure. 11799079 2002
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.100 Biomarker disease BEFREE GH effects were examined at early (4 months) and late (10 months) phases of disease in the cardiomyopathic (CM) hamster, and the combination of GH with chronic ACE inhibition was assessed in late-phase heart failure. 10525494 1999