|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
A 4-year-old boy presented with hypoglycemia and hyponatremia as associated with growth hormone (GH), thyroid stimulating hormone (TSH), and adrenocorticotropic hormone (ACTH) deficiencies.
|
31448886 |
2019 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
We conclude that GH acts through its receptor in the liver to activate autophagy, preserve triglycerides, enhance gluconeogenesis, and prevent hypoglycemia in calorie-restricted mice, a model of famine.
|
30910968 |
2019 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Epinephrine, cortisol, and growth hormone responses to hypoglycemia were lower in the IAH group (<i>P</i> < 0.05).
|
31455689 |
2019 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
However, whether GH modulates the CRR to hypoglycemia <i>via</i> specific neuronal populations is currently unknown.
|
31366244 |
2019 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Elevated insulin (8.3 ± 8.4 mIU/L), normal cortisol (15.5 ± 6.6 μg/dL [6-21]), normal growth hormone (18.8 ± 15.7 ng/mL [0.1-6.2]) and inappropriate low serum free fatty acids (0.3 ± 0.2 mmol/L [>1.5]) levels were measured during hypoglycemia (plasma glucose <50 mg/dL).
|
31465295 |
2019 |
|
Hypoglycemia
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Determining the different detection mechanisms, the phenotype of neurosecretion, and neural connections involving glucose-sensitive neurons is essential to understanding the response to hypoglycemia through modulation of food intake, thermogenesis, and activation of sympathetic and parasympathetic branches, inducing glucagon and epinephrine secretion and other hypothalamic-pituitary axis-dependent counterregulatory hormones, such as glucocorticoids and growth hormone.
|
29796992 |
2019 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
No significant changes of GLC, growth hormone (GH), cortisol (COR), epinephrine (E), and norepinephrine (NE) were found in both groups during hypoglycemia clamp test.
|
29032494 |
2018 |
|
Hypoglycemia
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
OTS showed a later rise in GH levels in response to hypoglycemia, compared to ATL, but not to NCS.
|
29157780 |
2018 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Through GHSR, ghrelin stimulates growth hormone (GH) secretion, a function that evolved to protect against starvation-induced hypoglycemia.
|
29233536 |
2018 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
PEGylation of IGF-I strongly enhances half-life, reduces the negative GH feedback and hypoglycemia potential, and therefore offers a valuable alternative to rhIGF-I in treatment of relevant diseases.
|
28110155 |
2017 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
HIIT suppressed cortisol and growth hormone responses, but not catecholamine responses to hypoglycemia.
|
28420673 |
2017 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
In non-pregnant (NP) animals, the GOAT-ghrelin-GH axis prevents hypoglycemia caused by caloric restriction (CR).
|
27701682 |
2017 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
The benefits of treating patients with SRS with growth hormone include improved body composition, motor development and appetite, reduced risk of hypoglycaemia and increased height.
|
27585961 |
2017 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Despite equivalent day 2 insulin (93 ± 6 pmol/L) and glucose levels (5.3 ± 0.1 mmol/L), plasma epinephrine, norepinephrine, glucagon, cortisol, and growth hormone responses were similarly reduced after alprazolam or day 1 hypoglycemia compared with euglycemic control.
|
27217489 |
2016 |
|
Hypoglycemia
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
The counter-regulatory hormones glucagon, epinephrine, norepinephrine, growth hormone and cortisol were appropriately suppressed when plasma glucose levels were >4.0 mmol/l (>72 mg/dl), but increased in the albiglutide and placebo groups with glucose levels <3.3 mmol/l (<59.4 mg/dl) in response to hypoglycaemia.
|
25263215 |
2015 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Cardiac function was rescued by replacement with hydrocortisone and thyroxine; hypoglycaemia stopped under growth hormone therapy.
|
22232309 |
2012 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
i) TS with GH deficiency should be considered as a potential differential diagnosis of hypoglycemia in infants requiring higher doses of GH. ii) While array CGH may be erroneous in quantification of TS mosaicism, it is useful in precisely delineating isochromosomes and identifying genes on them that escape X-inactivation and thus possibly affect the TS phenotype.
|
23426831 |
2012 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
The importance of the endogenous Goat/ghrelin system in the neuroendocrine adaptation to fasting was recently highlighted by the observation that acyl-ghrelin mediated elevation of growth hormone (GH) release prevents starvation induced hypoglycemia in Goat(-/-) mice.
|
21035823 |
2011 |
|
Hypoglycemia
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Thyroid-stimulating hormone, free thyroxine, and growth hormone (GH) levels were measured, and insulin-induced hypoglycemia and arginine infusion tests were done.
|
20061274 |
2010 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Imatinib or combinations of glucocorticoids and growth hormone are alternative palliative strategies for symptomatic hypoglycemia.
|
17229322 |
2007 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Subnormal growth hormone response was noted during hypoglycemia and pharmacologic stimuli with clonidine and levodopa.
|
11585376 |
2001 |
|
Hypoglycemia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Non-islet-cell tumor associated with hypoglycemia in a child: successful long-term therapy with growth hormone.
|
7658270 |
1995 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
In five of seven patients GH reached a mean peak of 12.6 +/- 4.2 micrograms/l after insulin-induced hypoglycemia, compared with 5 +/- 2.8 micrograms/l after GHRH.
|
8516423 |
1993 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Growth hormone response to insulin-induced hypoglycemia was somewhat blunted, but prolactin, cortisol, and thyroid-stimulating hormone responses were quite normal.
|
3917947 |
1985 |
|
Hypoglycemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
These consisted of: (1) growth retardation with height and weight below the third centiles; in the younger one at age 14, hypoglycaemia failed to elicit a rise in growth hormone but did so in the older one at age 17; (2) serum TSH was raised in the older one in whom serum FSH and LH were also above the normal range; and (3) myopathy characterised by pronounced dilatation of the sarcoplasmic reticulum was present in the younger one; distinct reduction of muscle strength was shown in his older brother with ultrastructural alteration of skeletal muscle of unknown significance.
|
604492 |
1977 |