Coronary Artery Disease
|
0.500 |
Biomarker
|
disease |
BEFREE |
Coronary Heart Disease and ABO Blood Group in Diabetic Women: A Case-Control Study.
|
31092877 |
2019 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
All patients were genotyped for 45 genome-wide significant CAD risk variants, including rs495828 at the ABO locus.
|
30837090 |
2019 |
Coronary Artery Disease
|
0.500 |
Biomarker
|
disease |
BEFREE |
Multiple linear regression analysis was performed to test the association between the severity of CAD and ABO blood groups.
|
31645856 |
2019 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Genetically instrumented blood lead was not associated with CAD (odds ratio (OR) 1.01 per effect size of log transformed blood lead, 95% confidence interval (CI) 0.97, 1.05), blood pressure (systolic -0.18 mmHg, 95% CI -0.44 to 0.08 and diastolic -0.03 mmHg, 95% CI -0.09 to 0.15) or diabetes (OR 0.98, 95% CI 0.92 to 1.03) using MR-PRESSO estimates corrected for an outlier SNP (rs550057) from the highly pleiotropic gene ABO.
|
31690775 |
2019 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Type non-O of the ABO blood group system has been associated with coronary artery disease, thrombosis, and a worse prognosis.
|
29958715 |
2018 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Association analyses based on false discovery rate implicate new loci for coronary artery disease.
|
28714975 |
2017 |
Coronary Artery Disease
|
0.500 |
Biomarker
|
disease |
BEFREE |
ABO blood group is a risk factor for coronary artery disease in patients with poor blood pressure control.
|
28513229 |
2017 |
Coronary Artery Disease
|
0.500 |
Biomarker
|
disease |
BEFREE |
Interestingly, haplotype analysis indicated that the QAGA or H4 haplotype of ADAMTS13 gene had a protective effect on CAD after adjustment for ABO blood group [odds ratio (OR) = 0.3, 95% confidence interval (CI) = 0.1, 0.6] and major CAD risk factors (OR = 0.3, 95% CI = 0.1, 0.7).
|
27536857 |
2017 |
Coronary Artery Disease
|
0.500 |
Biomarker
|
disease |
BEFREE |
The present study demonstrates that blood type O was independently and positively associated with an open culprit artery in patients with AMI, suggesting that the ABO blood type is not only associated with the susceptibility to coronary artery disease but also to spontaneous reperfusion in AMI patients.
|
28387531 |
2017 |
Coronary Artery Disease
|
0.500 |
Biomarker
|
disease |
BEFREE |
ABO blood groups have been confirmed to be associated with cardiovascular diseases such as coronary artery disease.
|
27988281 |
2017 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Genome-wide association studies (GWAS) identified several single nucleotide polymorphisms (SNPs) associated with coronary artery disease (CAD) and myocardial infarction (MI) locus in ABO gene.
|
27542834 |
2016 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Risk loci for ischemic stroke and its subtypes have been implicated in atrial fibrillation (PITX2 and ZFHX3), coronary artery disease (ABO, chr9p21, HDAC9, and ALDH2), blood pressure (ALDH2 and HDAC9), pericyte and smooth muscle cell development (FOXF2), coagulation (HABP2), carotid plaque formation (MMP12), and neuro-inflammation (TSPAN2).
|
27796860 |
2016 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
|
26343387 |
2015 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
It appears that only the ABO locus is a shared risk factor for coronary artery disease and VTE.
|
24745723 |
2014 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The ABO locus, also linked to CAD risk by the GWAS approach, is related to multiple phenotypes, including plasma interleukin-6 (IL-6) levels.
|
22902153 |
2013 |
Coronary Artery Disease
|
0.500 |
Biomarker
|
disease |
BEFREE |
Since distinct genome-wide association studies linked the ABO gene with myocardial infarction (MI) in the presence of coronary atherosclerosis and with coronary artery disease, these findings may not only enhance our understanding of adhesion molecule biology, but may also provide a focus for several novel research avenues.
|
23300549 |
2012 |
Coronary Artery Disease
|
0.500 |
Biomarker
|
disease |
CTD_human |
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
|
21378990 |
2011 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
ABO blood group alleles: A risk factor for coronary artery disease. An angiographic study.
|
20371059 |
2010 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Common variants in ABCG8 and ABO are strongly associated with serum phytosterol levels and show concordant and previously unknown associations with CAD.
|
20529992 |
2010 |