Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.360 Biomarker disease BEFREE LncRNA NEAT1 promotes docetaxel resistance in prostate cancer by regulating ACSL4 via sponging miR-34a-5p and miR-204-5p. 31672604 2020
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.360 AlteredExpression disease BEFREE The results showed that NEAT1 was significantly up-regulated in PCa tissues and PCa cell lines. 31481527 2019
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.360 AlteredExpression disease BEFREE By taking advantage of the prostate cancer tumor transcriptome profiles from The Cancer Genome Atlas, our data-mining pipeline identified a series of transcription factors (TF) whose regulatory activities on target genes depended on the level of NEAT1. 29871935 2018
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.360 Biomarker disease BEFREE The progressive emergence of the ERα and ERα-regulated genes (eg, progesterone receptor (PR), PS2, TMPRSS2-ERG fusion, and NEAT1) during prostate cancer progression and hormone refractory disease suggests that these tumors can bypass the AR by using estrogens and progestins for their growth. 29094395 2018
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.360 Biomarker disease CTD_human Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets. 29662167 2018
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.360 Biomarker disease BEFREE In function, NEAT1 promoted the prostate cancer cell growth through IGF1R/AKT signaling pathway. 29225160 2018
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.360 AlteredExpression disease BEFREE Prostate cancer cells expressing high levels of NEAT1 were recalcitrant to androgen or AR antagonists. 25415230 2014
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.320 Biomarker group BEFREE The effect of NEAT1 on tumor growth was observed in a mice model of transplanted hepatoma. 31819522 2019
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.320 AlteredExpression disease BEFREE The expression of transcript variants of NEAT1 and transcripts encoding the paraspeckle-associated proteins was analysed in the TCGA liver cancer data set. 30946555 2019
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.320 AlteredExpression disease BEFREE Our data showed that increase NEAT1_2 and SFPQ expressions in liver cancer specimens were associated with the development of cisplatin resistance; high SFPQ expression level impaired patients' survival from liver cancer. 30254462 2018
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.320 Biomarker group BEFREE The effect of NEAT1 on tumor growth was observed in mouse models of transplanted hepatoma. 28526689 2017
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.320 Biomarker group CTD_human Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. 27064257 2016
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.320 Biomarker disease CTD_human Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. 27064257 2016
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker group CTD_human Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets. 29662167 2018
CUI: C0087031
Disease: Juvenile-Onset Still Disease
Juvenile-Onset Still Disease
0.300 Biomarker disease CTD_human Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets. 19565504 2009
CUI: C3495559
Disease: Juvenile arthritis
Juvenile arthritis
0.300 Biomarker disease CTD_human Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets. 19565504 2009
CUI: C3714758
Disease: Juvenile psoriatic arthritis
Juvenile psoriatic arthritis
0.300 Biomarker disease CTD_human Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets. 19565504 2009
Polyarthritis, Juvenile, Rheumatoid Factor Negative
0.300 Biomarker disease CTD_human Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets. 19565504 2009
Polyarthritis, Juvenile, Rheumatoid Factor Positive
0.300 Biomarker disease CTD_human Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets. 19565504 2009
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute
0.110 Biomarker disease BEFREE Long noncoding RNA NEAT1 modulates cell proliferation and apoptosis by regulating miR-23a-3p/SMC1A in acute myeloid leukemia. 30246348 2019
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute
0.110 GeneticVariation disease GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.100 Biomarker disease BEFREE Identification of lncRNA NEAT1/miR-21/RRM2 axis as a novel biomarker in breast cancer. 31621912 2020
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 AlteredExpression group BEFREE Corrigendum to "Prognostic Effect of Long Noncoding RNA NEAT1 Expression Depends on p53 Mutation Status in Cancer". 31485225 2020
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.100 AlteredExpression disease BEFREE We found that NEAT1 expression was increased in CRC tissues and cells, which showed a negative correlation with miR-34a expression. 31802650 2020
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 Biomarker disease BEFREE Kaplan-Meier's analysis was performed to evaluate the relationship between NEAT1 and poor prognosis in GC. 31617275 2020