HIF1A, hypoxia inducible factor 1 subunit alpha, 3091

N. diseases: 1044; N. variants: 15
Disease: Angiogenic Switch ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1510885
Disease: Angiogenic Switch
Angiogenic Switch 		0.030 Biomarker disease BEFREE Induction of HIF-1α in tumor cells activates the angiogenic switch and allows for metabolic adaptations. 29628507 2018
CUI: C1510885
Disease: Angiogenic Switch
Angiogenic Switch 		0.030 Biomarker disease BEFREE HIF-1alpha plays a major role in the response of tumors to hypoxia, and it is mainly responsible for the "angiogenic switch". 16294030 2005
CUI: C1510885
Disease: Angiogenic Switch
Angiogenic Switch 		0.030 Biomarker disease BEFREE These results indicate that amplification of normal HIF-1-dependent responses to hypoxia via loss of p53 function contributes to the angiogenic switch during tumorigenesis. 10640274 2000