Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.030 Biomarker disease BEFREE These results reveal the underlying mechanism of Nur77 as a promising modifier gene in heart failure. 29850786 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.030 AlteredExpression disease BEFREE These findings show that Nur77 regulates <i>RLN3</i> expression, therefore suppressing apoptosis in the heart, and suggest that activation of Nur77 may represent a useful therapeutic strategy for inhibition of cardiac fibrosis and heart failure. 30006349 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.030 Biomarker disease BEFREE Detailed knowledge on the role of Nur77 in maintaining cardiomyocyte Ca(2+) homeostasis and the dual role Nur77 plays in cardiac remodelling will aid in developing personalized therapies against heart failure. 26486271 2015