Disease: Multiple Sclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.040 Biomarker disease BEFREE This finding indicates that Nr4a1-related molecule(s) may have therapeutic potential in MS and likely other autoimmune disorders. 28962999 2018
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.040 Biomarker disease BEFREE Our current data thus identify Nr4a1 as regulator of microglia activation and potentially new target for the treatment of inflammatory CNS diseases such as multiple sclerosis. 28411187 2017
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.040 AlteredExpression disease BEFREE Here we found that the transcription factor Nr4a1 regulated the production of norepinephrine (NE) in macrophages and thereby limited experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis. 26523867 2015
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.040 Biomarker disease BEFREE We demonstrated that the low apoptotic level in MS patients was repaired by Vit D(3) mainly through NR4A1 and to a lesser extent thorough BCL2-associated X protein (BAX). 21752397 2011