Disease: Hepatitis B ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 Biomarker disease BEFREE Targeting GRP78 may help develop to design novel therapeutic strategies against chronic HBV infection and the associated hepatocellular carcinoma (HCC). 31712392 2020
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 AlteredExpression disease BEFREE The results showed that the secretion of HBsAg (HBV surface antigen), HbeAg (HBV e antigen), and HBV DNA in HepG2.2.15 cells was significantly decreased by BET via suppression of GRP78 expression. 27144395 2016
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 AlteredExpression disease BEFREE Grp78 expression was down-regulated by HBV infection both in vitro and in liver tissues of patients. 27234046 2016
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 GeneticVariation disease BEFREE Our previous study indicated that a common variant (rs430397 G>A) in the intron 5 of glucose-regulated protein 78 (GRP78) gene was associated with risk and prognosis of primary hepatocellular carcinoma (HCC), including HBV- and cirrhosis-related HCC. rs430397 polymorphism may be a contributing factor or biomarker of HBV infection or HBV-related cirrhosis. 21779363 2011
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 GeneticVariation disease BEFREE These observations do not support a role for GRP78 polymorphisms in HBV infection in a predominantly Chinese Han population. 20525207 2010
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 Biomarker disease BEFREE To examine the association between -86 bp (T > A) in the glucose-regulated protein 78 gene (GRP78) and hepatitis B virus (HBV) invasion. 19842229 2009
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 Biomarker disease LHGDN Mammalian BiP controls posttranslational ER translocation of the hepatitis B virus large envelope protein. 18708056 2008
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 Biomarker disease LHGDN Molecular chaperone GRP78/BiP interacts with the large surface protein of hepatitis B virus in vitro and in vivo. 12552023 2003