HTR2A, 5-hydroxytryptamine receptor 2A, 3356

N. diseases: 60; N. variants: 1
Disease: Hyperalgesia, Thermal ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker phenotype CTD_human Four days after 2',3'-dideoxycytidine administration, rats had developed thermal allodynia as well as mechanical hyperalgesia and allodynia, which dose-dependently decreased after epidural injection of MDL 11,939, a 5-HT2A receptor antagonist. 17888573 2008
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker phenotype CTD_human Vincristine-treated rats (0.1mg/kg, daily i.p. administration for two 5-day cycles) developed thermal allodynia and mechanical hypersensitivity, which decreased in a dose-related manner after epidural injection a 5-HT2A receptor antagonist. 18930597 2008