HTR2C, 5-hydroxytryptamine receptor 2C, 3358

N. diseases: 140; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1524032
Disease: Depression and Suicide
Depression and Suicide
0.030 Biomarker disease BEFREE Changes in serotonin(2C) receptor (5-HTR2c) editing, splicing and density were found in conditions such as depression and suicide, but mechanisms explaining the changes in 5-HTR2c function are unknown. 23247076 2013
CUI: C1524032
Disease: Depression and Suicide
Depression and Suicide
0.030 Biomarker disease BEFREE The serotonin 2C receptor (5-HT 2C R) has been implicated in depression and suicide. 17848916 2008
CUI: C1524032
Disease: Depression and Suicide
Depression and Suicide
0.030 Biomarker disease BEFREE These findings are in accordance with the previous findings, and suggest that altered RNA editing of HTR2C may have some significance in major depression and suicide. 12853111 2003