Adult Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Collectively, the tenascin-C/TNIIIA2 could be a potential therapeutic target for glioblastoma.
|
31261783 |
2019 |
Adult Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Inhibition of the tenascin-C/β1-integrin axis may be a therapeutic target for glioblastoma, and peptide FNIII14 may represent a new approach for glioblastoma chemotherapy.
|
31189613 |
2019 |
Adult Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
We demonstrate the proximal localization of TNC and BTIC in human glioblastoma specimens and in orthotopic murine xenografts of human BTIC implanted intracranially.
|
28416488 |
2017 |
Adult Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Thus, we demonstrate dual activities for tenascin-C in glioblastoma angiogenesis and uncover potential targeting and prediction opportunities.
|
27926865 |
2016 |
Adult Glioblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Robust expression of TN-C was found within the tumor mass of surgery specimens from glioblastoma.
|
23963648 |
2013 |
Adult Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The latter is a DNA aptamer that can recognize the extracellular matrix protein tenascin-C on the surface of human glioblastoma cells.
|
24432373 |
2013 |
Adult Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Extracellular matrix of glioblastoma inhibits polarization and transmigration of T cells: the role of tenascin-C in immune suppression.
|
20622113 |
2010 |
Adult Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our results suggest that endogenous tenascin-C contributes the invasive nature of glioblastoma and the compositional change of brain tissue, which renders tenascin-C as a prime candidate for anti-invasion therapy for glioblastoma.
|
19459858 |
2009 |
Adult Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Tenascin-C is an extracellular matrix protein known to correlate with prognosis in patients with glioblastoma, probably by stimulation of invasion and neoangiogenesis.
|
16292494 |
2006 |
Adult Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Recently, tenascin-C (TN-C) as a dominant epitope in glioblastoma has been discovered.
|
16775434 |
2006 |
Adult Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Distribution pattern of tenascin-C in glioblastoma: correlation with angiogenesis and tumor cell proliferation.
|
16388320 |
2005 |
Adult Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
To determine if a reduction in the expression level of caveolin-1 mRNA and protein accompanied the transformation of astrocytes, we undertook studies of two transformed rat astroglial cell lines, C6 and DI TNC(1), as well as several cell lines derived from human glioblastoma tumors: T98G, U87MG, U118MG, U138MG, and U373MG.
|
11857686 |
2002 |
Adult Glioblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
To identify an aptamer for testing as a tumor-selective ligand, SELEX (systematic evolution of ligands by exponential enrichment) procedures were performed using both TN-C and TN-C-expressing U251 glioblastoma cells.
|
11590140 |
2001 |