Inflammatory Bowel Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
ICAM-1 is an adhesion molecule which is upregulated on endothelial cells during IBD, thereby mediating the adhesion and migration of leucocytes from blood to sites of active inflammation.
|
31068803 |
2019 |
Inflammatory Bowel Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
Our results demonstrate that ICAM-1-modified mesenchymal stem cells (MSCs) remarkably alleviate inflammatory damage in IBD mice by promoting MSC homing to the target and immune organs.
|
31443680 |
2019 |
Inflammatory Bowel Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
Specific blockade of the endothelial ligands intercellular adhesion molecule-1 [ICAM-1] and mucosal addressin cell adhesion molecule [MAdCAM] involved in leukocyte recruitment to the site of inflammation as therapeutic targets in inflammatory bowel disease [IBD] has been recognized from their overexpression in the inflamed mucosa and successful intervention based on these ligands in preclinical animal models.
|
29757363 |
2018 |
Inflammatory Bowel Diseases
|
0.400 |
Biomarker
|
group |
CTD_human |
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.
|
28067908 |
2017 |
Inflammatory Bowel Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The polymorphisms K469E and G261R of intercellular adhesion molecule-1 and susceptibility to inflammatory bowel disease: a meta-analysis.
|
25942347 |
2015 |
Inflammatory Bowel Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Our results support previous findings about participation of mutations of NOD2 and ICAM-1 genes in IBD.
|
18647548 |
2008 |
Inflammatory Bowel Diseases
|
0.400 |
AlteredExpression
|
group |
BEFREE |
The treatment with the vitamin D derivatives, alone or in combination with LPS or TNF-alpha, significantly decreases ICAM-1 levels both in healthy subjects and IBD patients.
|
18200516 |
2008 |
Inflammatory Bowel Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
In the second approach, we typed four nonsynonymous polymorphisms in genes C3 (R102G and L314P) and ICAM1 (G241R and K469E) in four independent cohorts totaling 2178 IBD cases.
|
16570073 |
2006 |
Inflammatory Bowel Diseases
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Colonic epithelial cell expression of ICAM-1 relates to loss of surface continuity: a comparative study of inflammatory bowel disease and colonic neoplasms.
|
16497620 |
2006 |
Inflammatory Bowel Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The aim of this study was to investigate polymorphisms in the NOD2/CARD15 (R702W, G908R, and 3020insC), NOD1/CARD4 (E266K, D372N), and ICAM-1 (G241R, K469E) genes, which are known to be associated with inflammation, in Turkish patients with inflammatory bowel disease and healthy control groups.
|
16741608 |
2006 |
Inflammatory Bowel Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
ICAM-1 gene lies on chromosome 19p13, implicated in determining susceptibility to IBD.
|
15638228 |
2005 |
Inflammatory Bowel Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
Inflammatory bowel disease is linked to 19p13 and associated with ICAM-1.
|
15290909 |
2004 |
Inflammatory Bowel Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
Intercellular adhesion molecule 1 gene lies on chromosome 19p13, implicated in determining susceptibility to inflammatory bowel disease.
|
15334773 |
2004 |
Inflammatory Bowel Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Intercellular adhesion molecule-1 (ICAM-1, CD54) gene polymorphisms have been implicated in the susceptibility to a range of inflammatory diseases, including inflammatory bowel disease (IBD).
|
15123348 |
2004 |
Inflammatory Bowel Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
We identified an overall association between IBD and ICAM-1 K469 in a Japanese population.
|
12477764 |
2003 |
Inflammatory Bowel Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Polymorphisms of the ICAM-1 gene are associated with inflammatory bowel disease, regardless of the p-ANCA status.
|
11726228 |
2001 |
Inflammatory Bowel Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Intercellular adhesion molecule-1 (ICAM-1) gene polymorphisms have been implicated in the susceptibility to inflammatory diseases, including multiple sclerosis and inflammatory bowel disease.
|
10792421 |
2000 |
Inflammatory Bowel Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
This is the first time that the polymorphisms of HLA-DR and -DQ, tumour necrosis factor (TNF), E-selectin (CD62E), L-selectin (CD62L), and intercellular adhesion molecule 1 (ICAM-1, CD54) were determined in Estonians, a population with a low IBD incidence rate, and their occurrence investigated in subgroups of a total of 53 IBD patients.
|
10563674 |
1999 |
Inflammatory Bowel Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The aim of this study was to examine potential associations of intercellular adhesion molecule 1 (ICAM-1) gene polymorphisms with inflammatory bowel disease or subsets of inflammatory bowel disease.
|
7615193 |
1995 |