IFNGR1, interferon gamma receptor 1, 3459

N. diseases: 153; N. variants: 30
Disease: Leishmaniasis, Visceral ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023290
Disease: Leishmaniasis, Visceral
Leishmaniasis, Visceral 		0.020 AlteredExpression disease BEFREE This study aimed to identify putative functional polymorphisms in the IFNGR1 gene, and to determine whether differences in expression of interferon-γ (IFNG) and IFNGR1 at the RNA level are associated with pathogenesis of VL and/or PKDL in Sudan. 25466928 2014
CUI: C0023290
Disease: Leishmaniasis, Visceral
Leishmaniasis, Visceral 		0.020 Biomarker disease BEFREE Hence, polymorphism in a type 2 cytokine gene influences underlying susceptibility to VL, whereas IFNGR1 is specifically related to susceptibility to PKDL. 12847550 2003